The study of sperm energy metabolism measured using 13C magnetic resonance spectroscopy

The study of sperm energy metabolism measured using 13C magnetic resonance spectroscopy

Studying energy metabolism in sperm may be helpful in understanding the relationship between poor sperm motility and infertility. Sperm motility is fuelled by Adenosine triphosphate (ATP). Main ATP related production pathways are anaerobic glycolysis and oxidative phosphorylation (OXPHOS). These pat...

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Bibliographic Details
Main Author: Nurul Fadhlina Ismail (Author)
Format: Thesis Book
Language:English
Subjects:
The University of Sheffied -- > Dissertations
Magnetic Resonance
Dissertations, Academic
Metabolism
Spermatozoa
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Table of Contents:
  • 1. Introduction to spermatozoa and MRS
  • 2. Materials and methods
  • 3. Preliminary experiments
  • 4. The effect of metabolic inhibitors on sperm metabolism and vitality
  • 5. Effects of temperature, labelled substrate and inhibitors
  • 6. Sperm metabolism measured using hyperpolarised 2-13C pyruvate
  • 7. The effect of oxygen concentration on sperm metabolism
  • 8. General discussion, conclusions and future work

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