Distinct microrna and gene expression-pathway based analysis in association with clinical and laboratory features of acute promyelocytic leukaemia

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Bibliographic Details
Main Author: Imilia Ismail (Author)
Format: Thesis Book
Language:English
Subjects:
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Table of Contents:
  • 1. Introduction
  • 2. Literature review
  • 3. Materials and methods
  • 4. Demographic data and clinical characteristics of APL
  • 5. Microrna expression profiling and in silico analysis of targeted genes regulated by differential expression of microrna in APL patients
  • 6. Analysis of gene expression profiles and pathways involved in the pathogenesis of APL
  • 7. Mutation detection of FLT3/ITD and NPM1 genes in APL patients and the association with clinical and laboratory features of APL
  • 8. Association between MIR-100 and FLT3 with clinical and laboratory features of newly diagnosed APL patients
  • 9. Conclusion and future recomendation