The effect of Nigella Sativa linn on cAMP & Mu-opioid receptor protein levels in morphine-treated U-87 MG cell line

Prolonged use of opioid will cause physical dependence to an individual, while abrupt termination of opioid or the administration of an antagonist lead to the symptoms of withdrawal. Physical dependence is manifested by the occurrence of withdrawal sign and symptoms such as the increase in the conce...

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Bibliographic Details
Main Author: Nor Zidah Ahmad (Author)
Format: Thesis Book
Language:Malay
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Summary:Prolonged use of opioid will cause physical dependence to an individual, while abrupt termination of opioid or the administration of an antagonist lead to the symptoms of withdrawal. Physical dependence is manifested by the occurrence of withdrawal sign and symptoms such as the increase in the concentration of cyclic adenosine monophosphate (cAMP) level, following chronic exposure to morphine. Nowadays, many opioid substitution therapies exist aiming to treat opioid dependence, where the main purpose of these therapies is to control withdrawal symptoms.
Physical Description:xvi, 137 leaves; 31 cm.
Bibliography:Includes bibliographical references (leaves 111-131)