The effect of Nigella Sativa linn on cAMP & Mu-opioid receptor protein levels in morphine-treated U-87 MG cell line
Prolonged use of opioid will cause physical dependence to an individual, while abrupt termination of opioid or the administration of an antagonist lead to the symptoms of withdrawal. Physical dependence is manifested by the occurrence of withdrawal sign and symptoms such as the increase in the conce...
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| Format: | Thesis Book |
| Language: | Malay |
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| LEADER | 01859cam a2200325 7i4500 | ||
|---|---|---|---|
| 001 | 0000098075 | ||
| 005 | 20210803090000.0 | ||
| 008 | 200309s2019 my may | ||
| 040 | |a UniSZA | ||
| 060 | 0 | 0 | |a WB 925 |b N822e 2020 |
| 090 | 0 | 0 | |a WB 925 |b N822e 2020 |
| 100 | 0 | |a Nor Zidah Ahmad |e author | |
| 245 | 1 | 4 | |a The effect of Nigella Sativa linn on cAMP & Mu-opioid receptor protein levels in morphine-treated U-87 MG cell line |c Nor Zidah Ahmad. |
| 264 | 0 | |c 2019. | |
| 300 | |a xvi, 137 leaves; |c 31 cm. | ||
| 336 | |a text |2 rdacontent | ||
| 337 | |a unmediated |2 rdamedia | ||
| 338 | |a volume |2 rdacarrier | ||
| 502 | |a Thesis ( Degree of Master of Science) - Universiti Sultan Zainal Abidin, 2019 | ||
| 504 | |a Includes bibliographical references (leaves 111-131) | ||
| 505 | 0 | |a 1. Introduction -- 2. Literature review -- 3. Methodology -- 4. Results -- 5. Discussion -- 6. Conclusion and recommendation | |
| 520 | |a Prolonged use of opioid will cause physical dependence to an individual, while abrupt termination of opioid or the administration of an antagonist lead to the symptoms of withdrawal. Physical dependence is manifested by the occurrence of withdrawal sign and symptoms such as the increase in the concentration of cyclic adenosine monophosphate (cAMP) level, following chronic exposure to morphine. Nowadays, many opioid substitution therapies exist aiming to treat opioid dependence, where the main purpose of these therapies is to control withdrawal symptoms. | ||
| 610 | 0 | 0 | |a Universiti Sultan Zainal Abidin -- |x Faculty of Medicine |
| 610 | 0 | 0 | |a Universiti Sultan Zainal Abidin -- |x Dissertations |
| 650 | 0 | |a Morphine | |
| 650 | 0 | |a Nigella sativa | |
| 650 | 0 | |a Cell Line | |
| 650 | 0 | |a Dissertations, Academic | |
| 710 | 2 | |a Universiti Sultan Zainal Abidin | |
| 999 | |a 1000178969 |b Thesis |c Reference |e Medical Thesis Collection | ||