The effectiveness of budesonide nasal irrigation in allergic rhinitis patient
Introduction: Allergic rhinitis (AR) is a long-standing disease and has been shown to cause significant impairments in patient?s quality of life. Saline nasal irrigation is a proven adjunct treatment for AR. He addition of steroid in the saline solution can provide local steroid effect and thus incr...
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| 语言: | English |
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| LEADER | 02761cam a2200337 7i4500 | ||
|---|---|---|---|
| 001 | 0000100013 | ||
| 005 | 20210418090000.0 | ||
| 008 | 210316s2020 my eng | ||
| 040 | |a UniSZA | ||
| 060 | 0 | 0 | |a WV 335 |b M952e 2020 |
| 090 | 0 | 0 | |a WV 335 |b M952e 2020 |
| 100 | 0 | |a Muhammad Nu'aim Ishak | |
| 245 | 1 | 4 | |a The effectiveness of budesonide nasal irrigation in allergic rhinitis patient |c Muhammad Nu'aim bin Ishak. |
| 264 | 0 | |c 2020. | |
| 300 | |a vi, 91 leaves; |c 31 cm. | ||
| 336 | |a text |2 rdacontent | ||
| 337 | |a unmediated |2 rdamedia | ||
| 338 | |a volume |2 rdacarrier | ||
| 502 | |a Thesis (Degree of Master of Medicine) - Universiti Sains Malaysia, 2020 | ||
| 504 | |a Includes bibliographical references (leaves 67-71) | ||
| 505 | 0 | |a 1. Introduction -- 2. Objectives of the study -- 3.Manuscript -- 4. Study protocol | |
| 520 | |a Introduction: Allergic rhinitis (AR) is a long-standing disease and has been shown to cause significant impairments in patient?s quality of life. Saline nasal irrigation is a proven adjunct treatment for AR. He addition of steroid in the saline solution can provide local steroid effect and thus increase the effectiveness of this technique. Objective: Our study aimed to determine the effectiveness of budesonide nasal irrigation as an adjunct treatment for AR, compared to saline nasal irrigation. Methods: This was a randomized controlled study involving 99 patients diagnosed with AR, where half of them were treated with saline nasal irrigation and another half treated with budesonide nasal irrigation. Parameters measured include Sino-nasal Outcome Test (SNOT-22) questionnaire, endoscopic nasal examination, and blood eosinophil count. Results: Patients treated with budesonide nasal irrigation had significant improvement in all the symptoms listed in the SNOT-22 questionnaire (P<0.001) and better outcome of endoscopic nasal examination findings, especially the nasal mucosa edema and secretion (P<0.001). However, there was no significant improvement of blood eosinophil count neither for a patient treated with budesonide nasal irrigation (P=0.091) nor for patient treated with saline nasal irrigation. (P=0.527). Conclusions: Budesonide nasal irrigation is effective s as an adjunct treatment for AR compared to saline nasal douching. | ||
| 610 | 0 | 0 | |a Universiti Sains Malaysia -- |x Dissertations |
| 650 | 0 | |a Dissertations, Academic | |
| 650 | 0 | |a Budesonide | |
| 650 | 0 | |a Nasal Lavage | |
| 650 | 0 | |a Rhinitis, Allergic | |
| 710 | 2 | |a Universiti Sains Malaysia | |
| 999 | |a 1000182247 |b Thesis |c Reference |e Medical Bibliographic & Index Unit | ||
| 999 | |a 1000182248 |b CD-ROM |c Reference |e Medical Bibliographic & Index Unit | ||
| 999 | |a 1000182250 |b CD-ROM |c Reference |e Medical Bibliographic & Index Unit | ||