Effects of ticlopidine on metoprolol pharmacokinetics in major CYP2D6 genotypes within Malaysian subjects with cardiovascular diseases /
Ticlopidine is used as an anti-platelet drug in patients with ischaemic heart disease. An in vitro study suggested that ticlopidine inhibited CYP2D6 and the widely used antianginal metoprolol is metabolized by this polymorphic enzyme. The objective of this study to investigate the effect of ticlopid...
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| 格式: | Thesis |
| 语言: | English |
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Kuantan, Pahang :
Kulliyyah of Medicine, International Islamic University Malaysia,
2010
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| 在线阅读: | Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library. |
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