Prevalence of breast cancer and its associated factors for recurrence in Hospital Tengku Ampuan Afzan from 2008 to 2012 /

Breast cancer is the commonest malignancy in Malaysian women. Cancer recurrence has been a detrimental factor towards survival with peak of recurrence recorded in first 2 years of diagnoses. Identifying the prognostic factors towards recurrence is important to management and prolonging survival. We...

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主要作者: Azhani binti Chik
格式: Thesis
語言:English
出版: Kuantan, Pahang : Kulliyyah of Medicine, International Islamic University Malaysia, 2016
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040 |a UIAM  |b eng 
041 |a eng 
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050 |a RC280.B8 
100 0 |a Azhani binti Chik 
245 1 |a Prevalence of breast cancer and its associated factors for recurrence in Hospital Tengku Ampuan Afzan from 2008 to 2012 /  |c by Azhani binti Chik 
260 |a Kuantan, Pahang :  |b Kulliyyah of Medicine, International Islamic University Malaysia,  |c 2016 
300 |a xii, 36 leaves :  |b ill. ;  |c 30cm. 
502 |a Thesis (MOS)--International Islamic University Malaysia, 2016. 
504 |a Includes bibliographical references (leaves 30-33). 
520 |a Breast cancer is the commonest malignancy in Malaysian women. Cancer recurrence has been a detrimental factor towards survival with peak of recurrence recorded in first 2 years of diagnoses. Identifying the prognostic factors towards recurrence is important to management and prolonging survival. We have retrospectively analyzed 179 patients women with breast cancer based on 5 years single centre database with minimum follow up of 2 years. The demographic and clinicopathological characteristics were determined using descriptive statistics. Survival were calculated based on Kaplan- Meier method and multivariate analysis by Cox proportional hazards was performed to evaluate the potential factors affecting breast cancer recurrence. Mean follow up was 42 months, with mean age 52 years and 60.9% presented in Stage II disease. Overall recurrence was 41.9% with local recurrence 2.1%, regional recurrence 12.3% and distant recurrence 27.4%. 50% of our patients developed recurrence at 25 months. On univariate analysis, time to first presentation was significantly correlated with recurrence, while in multivariate analysis tumor size, lymph node positive and lymphovascular invasion were independently associated with recurrence. 
596 |a 1 6 
610 |a Hospital Tengku Ampuan Afzan 
650 0 |a Breast  |v Case studies  |x Cancer 
655 |a Theses, IIUM local 
690 |a Dissertations, Academic  |x Department of Surgery  |z IIUM 
710 |a International Islamic University Malaysia.  |b Department of Surgery 
856 |u https://lib.iium.edu.my/mom/services/mom/document/getFile/4Ku1wrrTMaONexBJfFQ6JL5T1NTvNwAX20161108150454422  |z Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library. 
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