Site-directed mutagenesis for the production of mutant TP53 Gene and analysis of its tumor suppressor activity /
As a cellular gatekeeper, p53 plays a major role in maintaining the cellular homeostasis. The existence of mutations may change the gene conformation and may affect its major function as the regulator of the cell proliferation. The p53 therapy based approach is a good candidate for treatment of TP53...
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| 格式: | Thesis |
| 语言: | English |
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Kuantan :
Kulliyyah of Pharmacy, International Islamic University Malaysia,
2011
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| 在线阅读: | Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library. |
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