rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Staphylococcal cassette chroromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients attending Tengku Ampuan Afzan Hospital (HTAA) in Kuantan, Pahang, Malaysia
  name:
    name part: Alarosi, Nasreen Mohammad
    role:
      role term: creator
  name:
    name part: International Islamic University Malaysia
    name part: Department of Basic Medical Sciences
  genre: Theses, IIUM local
  origin info:
    place:
      place term: my
    place:
      place term: Kuantan
    publisher: Kulliyyah of Medicine, International Islamic University Malaysia
    date issued: 2011
  language:
    language term: eng
  physical description:
    extent: xiv, 80 leaves : ill. charts; 30cm.
  abstract: Staphylococcus aureus is a major human pathogen. It causes a wide range of infections in the hospital setting as well as in the community environment. A broad variety of infections, ranging from minor pyodermas to life-threatening infections can be caused by S. aureus.The adaptive power of S. aureus to antibiotics lead to the emergence of methicillin-resistant S. aureus (MRSA) in the early 1960s. The cause of resistance to methicillin is the acquisition of the mecA gene, which is situated on a mobile genetic element, the staphylococcal cassette chromosome mec (SCCmec). Five major variants of SCCmec, types I to V, are distinguished. One of the most important techniques used to investigate the molecular epidemiology of S. aureus is SCCmec typing. This technique has been used to study the evolution of the MRSA and to study their subsequent worldwide dissemination.This study was conducted to determine the molecular typing of methicillin-resistant S.aureus (MRSA) organisms isolated by the Bacteriology Laboratory in Hospital TengkuAmpuanAfzan (HTAA), Kuantan, Pahang, Malaysia from inpatients admitted during the period from 1stApril to 30th September, 2010. A total of 28 MRSA isolates were re-identified by known bacteriological methods and the minimal inhibitory concentration (MIC) of oxacillin was determined by E-test. The antibiotic susceptibility was tested, by disc diffusion method to 7 different antibiotics as recommended by the National Committee for Clinical Laboratory Standards (NCCLS).Resistance to oxacillin was 100%,erythromycin 82.1%, gentamicin75%, tetracycline 78.6%, and trimethoprimsulfamethoxazole78.6%. None of the isolates was resistant to vancomycin or chloramphenicol. All isolates showed an MIC >4μg/mL. All 28 MRSA isolates were subjected to SCCmec typing by duplex real time PCR, 78.5%(22/28) were shown to possess SCCmec-III and 21.5% (6/28) were of type IV. This confirms observations in several other neighboring Far Eastern countries and corroborates the…
  note: by Nasreen Mohammad Alarosi
  note: Abstracts in English and Arabic.
  note: "A dissertation submitted in partial fulfillment of the requirement for the degree of Master of Medical Sciences."--On t.p.
  note: Thesis (MMDSC)--International Islamic University Malaysia, 2011.
  note: Includes bibliographical references (leaves 71-80).
  subject:
    geographic code: a-my---
  subject:
    topic: Staphylococcus aureus infections
    geographic: Malaysia Pahang
  subject:
    topic: Staphylococcal infections
    geographic: Malaysia Pahang
  subject:
    topic: Methicillin resistance
    geographic: Malaysia Pahang
  subject:
    topic: Staphylococcus aureus
    geographic: Malaysia Pahang
  classification: QR201.S68
  identifier: https://lib.iium.edu.my/mom/services/mom/document/getFile/aUAZT6bwZ0OvDUTLd4DpkEu1QqP9YE9X20130513100402434
  record info:
    record content source: UIAM
    record creation date: 120629
    language of cataloging:
      language term: eng