Analytical study on articular cartilage tissue engineering research : its ethico-legal aspects from Islamic perspective /

Degenerative joint disease has no known cure. Although this medical condition affects mostly the ageing population, joint injuries at a young age may accelerate the degeneration process. The existing pharmacological and surgical treatments alleviate symptomatic pain and help patients to remain activ...

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Bibliographic Details
Main Author: Muhammad Aa'zamuddin Ahmad Radzi (Author)
Format: Thesis
Language:English
Published: Kuantan, Pahang : Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, 2020
Subjects:
Online Access:http://studentrepo.iium.edu.my/handle/123456789/10023
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040 |a UIAM  |b eng  |e rda 
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050 4 |a R857.T55 
100 |a Muhammad Aa'zamuddin Ahmad Radzi  |e author  |9 5564 
245 1 0 |a Analytical study on articular cartilage tissue engineering research :  |b its ethico-legal aspects from Islamic perspective /  |c by Muhammad Aa'zamuddin bin Ahmad Radzi 
264 1 |a Kuantan, Pahang :  |b Kulliyyah of Allied Health Sciences, International Islamic University Malaysia,  |c 2020 
300 |a xviii, 330 leaves :  |b illustrations ;  |c 30cm. 
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347 |2 rdaft  |a text file  |b PDF 
500 |a Abstracts in English and Arabic. 
500 |a "A thesis submitted in fulfilment of the requirement for the degree of Doctor of Philosophy in Health Sciences." --On title page. 
502 |a Thesis (Ph.D)--International Islamic University Malaysia, 2020. 
504 |a Includes bibliographical references (leaves 239-292). 
520 |a Degenerative joint disease has no known cure. Although this medical condition affects mostly the ageing population, joint injuries at a young age may accelerate the degeneration process. The existing pharmacological and surgical treatments alleviate symptomatic pain and help patients to remain active. Unfortunately, there is no single treatment that is able to address the root cause of the disease thoroughly. As an alternative, tissue engineering and regenerative medicine (TERM) method offer numerous options to treat joint diseases. There are growing demands for tissue-engineered medical products (TEMPs) worldwide, including Malaysia. However, based on a scoping review, scientific development and clinical translation activities for TEMPs are not progressing as they should be. These multitude limitations perhaps stemmed from many challenges in TERM practices ranging from scientific and technical issues, economic recession, social perplexities, as well as ethical and legal issues. This study aims to formulate an ethical and legal framework to facilitate both scientific and social progress of articular cartilage tissue engineering (ACTE) research in Malaysian context. A survey on the worldwide trend of ACTE research was conducted using a systematic search and through content analysis in formulating the framework. This ethical and legal framework is addressed from the Islamic perspective. A framework, with the benefits being weighed up against possible risks and harmful effects, should be the basis of the practices of ACTE research. Since both ethics and scientific knowledge play a role to determine the permissibility of ACTE research, this study uses both scientific as well as ethical and legal literature, so the two disciplines are bridged. It is so because the concerns made by the bioethicists in this matter are worthy. While scientific endeavours done by the researchers to improve the scientific knowledge in ACTE is also worthy, these two concerns are thus complementary, not contradictory to each other. Although the monitoring by responsible bodies such as governments, legislators, and scientific organisations is essential, it equally is the responsibility of a competent TERM professional to be morally aware when confronted with issues related to ACTE research. More intellectual and engaging deliberation on ACTE research should enter the domain of ongoing moral, ethical and legal education. The end goal of this effort is towards establishing a holistic healthcare management model for patients in the future. 
650 0 |a Tissue engineering  |x Research  |z Malaysia  |9 5570 
650 0 |a Tissue engineering  |x Religious aspects  |x Islam  
655 7 |a Theses, IIUM local 
690 |a Dissertations, Academic  |x Kulliyyah of Allied Health Sciences   |z IIUM  |9 5571 
700 1 |a Abdurezak Abdulahi Hashi ,  |e degree supervisor  |9 5572 
700 0 |a Munirah Sha'ban,  |e degree supervisor  |9 5573 
710 2 |a International Islamic University Malaysia.  |b Kulliyyah of Allied Health Sciences  |9 2190 
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