Perioperative hyperglycaemia as a risk factor for early surgical-site infection in stable trauma patients in orthopaedic unit /

This study is to evaluate the association between perioperative hyperglycaemia and early surgical-site infection (SSI) in stable trauma patients with orthopaedic injuries. This is an observational cohort study conducted in Hospital Sultanah Nur Zahirah, Kuala Terengganu over 15 months. Patients age...

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Bibliographic Details
Main Author: Mohd Darulnizam bin Othman (Author)
Format: Thesis
Language:English
Published: Kuantan, Pahang : Kulliyyah of Medicine, International Islamic University Malaysia, 2019
Subjects:
Online Access:Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library.
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040 |a UIAM  |b eng  |e rda 
041 |a eng 
043 |a a-my--- 
100 0 |a Mohd Darulnizam bin Othman,  |e author 
245 1 |a Perioperative hyperglycaemia as a risk factor for early surgical-site infection in stable trauma patients in orthopaedic unit /  |c by Mohd Darulnizam bin Othman 
264 1 |a Kuantan, Pahang :  |b Kulliyyah of Medicine, International Islamic University Malaysia,  |c 2019 
300 |a xii, 50 leaves :  |b illustrations ;  |c 30cm. 
336 |2 rdacontent  |a text 
337 |2 rdamedia  |a unmediated 
338 |2 rdacarrier  |a volume 
338 |2 rdacarrier  |a online resource 
347 |2 rdaft  |a text file  |b PDF 
500 |a Abstracts in English. 
500 |a "A dissertation submitted in fulfilment of the requirement for the degree of Master of Orthopaedic Surgery." --On title page. 
502 |a Thesis (MORTH)--International Islamic University Malaysia, 2019. 
504 |a Includes bibliographical references (leaves 40-43). 
520 |a This study is to evaluate the association between perioperative hyperglycaemia and early surgical-site infection (SSI) in stable trauma patients with orthopaedic injuries. This is an observational cohort study conducted in Hospital Sultanah Nur Zahirah, Kuala Terengganu over 15 months. Patients age of 18 years and older with operative orthopaedic injuries were included in this study. Patients with steroid use, multisystem injuries, critically ill or unstable and patients with perioperative infection were excluded. Demographics, medical comorbidities, body mass index, type of fracture, HbA1c level in diabetic patients and length of hospital stay were recorded. Finger prick glucose values were obtained twice daily. Perioperative hyperglycaemia was defined by hyperglycaemic index (HGI) greater than 1.76 during the hospital stay. SSI was defined by gross intraoperative signs of infection or positive intraoperative culture at reoperation within 30 days, gross purulent discharged or superficial infection requiring an intravenous antibiotic. The categorical data were analysed using the chi-square test while continuous data were analysed using T-test. A total of 90 patients were enrolled in which 15 were diabetic and 75 were non-diabetic. Among hyperglycaemia patients, 10 patients were diabetic and only one was non-diabetic (p = <0.001). Perioperative hyperglycaemia was associated with mean age 54.3 year old, having one or more co-morbidity or mean admission glucose 13.1 mmol/L (p = <0.001). There were 12 early SSI giving an infection rate of 13.3%. Early SSI was associated with HGI 1.76 and more (p = <0.001), patients with 1 or more co-morbidity (p = 0.006), mean admission glucose of 9.63 mmol/L (p = <0.001). These study concluded that perioperative hyperglycaemia in stable trauma patients with orthopaedic injuries was associated with early SSI. 
596 |a 6 
655 7 |a Theses, IIUM local 
690 |a Dissertations, Academic  |x Department of Orthopaedics,Traumatology & Rehabilitation  |z IIUM 
700 0 |a Ahmad Fadzli Sulong,  |e degree supervisor 
700 0 |a Nazri Mohd Yusof,  |e degree supervisor 
700 0 |a Mohd Shukrimi Awang,  |e degree supervisor 
710 2 |a International Islamic University Malaysia.  |b Department of Orthopaedics,Traumatology & Rehabilitation 
856 4 |u http://studentrepo.iium.edu.my/handle/123456789/10344  |z Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library. 
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