Dielectrophoretic Manipulation For Cancer Cell Diagnostics

In this study of dielectrophoretic manipulation for cancer diagnostics, a few milestones had been achieved. First, the optimal experimental settings towards establishing a suitable experimental template for conducting dielectrophoretic characterisation experiments of MDA-MB-231 breast cancer cells o...

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Bibliographic Details
Main Author: Chan, Jun Yuan
Format: Thesis
Published: 2019
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Summary:In this study of dielectrophoretic manipulation for cancer diagnostics, a few milestones had been achieved. First, the optimal experimental settings towards establishing a suitable experimental template for conducting dielectrophoretic characterisation experiments of MDA-MB-231 breast cancer cells on a curved microelectrode platform were determined. Second, the dielectrophoretic characterisation of MDA-MB-231 breast cancer cells in different DMEM suspending medium concentrations on a curved microelectrode platform using the experimental template was established. Third, the dielectrophoretic responses and morphological changes of the MDA-MB-231 breast cancer cells from the dielectrophoretic characterisation experiments were analysed with the help of electric field simulation of microenvironment conditions and analysis of cell diameter measurements.