Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis

This study was conducted to determine the potential effects and toxicity associated with the use of Hylocereus Polyrhizus on blood parameters in mice. Two groups of six mice were given either the flesh with seed extract of HP (treatment group) or normal saline (control group).The flesh with seed ext...

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Main Author:	Darnalis, Nur Mardhiya
Format:	Thesis
Language:	English
Published:	2007
Subjects:	Examination of the blood RS Pharmacy and materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/100069/1/100069.PDF
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id	my-uitm-ir.100069
record_format	uketd_dc
spelling	my-uitm-ir.1000692024-08-26T05:05:17Z Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis 2007 Darnalis, Nur Mardhiya Examination of the blood RM Therapeutics. Pharmacology RS Pharmacy and materia medica This study was conducted to determine the potential effects and toxicity associated with the use of Hylocereus Polyrhizus on blood parameters in mice. Two groups of six mice were given either the flesh with seed extract of HP (treatment group) or normal saline (control group).The flesh with seed extract of Hylocereus polyrhizus was administered by gavage with the use of oral needle. Blood samples were obtained by cardiac puncture. No mortality and clinical signs of toxicity were observed upon administration of HP for both acute and sub acute toxicity studies. Blood analysis showed significant changes in certain blood parameters. In the acute toxicity study, the blood levels of urea were significantly lower in the treatment group. In the sub acute toxicity study, there were no significance differences between both groups for all parameters. It can be concluded that the flesh's extract of HP can affect certain blood parameters and possibly has hepatoprotective effects. Further studies are needed to validate these effects in order to ensure the safe consumption of HP fruit. 2007 Thesis https://ir.uitm.edu.my/id/eprint/100069/ https://ir.uitm.edu.my/id/eprint/100069/1/100069.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Sulong, Adnan
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Sulong, Adnan
topic	Examination of the blood Examination of the blood RS Pharmacy and materia medica
spellingShingle	Examination of the blood Examination of the blood RS Pharmacy and materia medica Darnalis, Nur Mardhiya Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
description	This study was conducted to determine the potential effects and toxicity associated with the use of Hylocereus Polyrhizus on blood parameters in mice. Two groups of six mice were given either the flesh with seed extract of HP (treatment group) or normal saline (control group).The flesh with seed extract of Hylocereus polyrhizus was administered by gavage with the use of oral needle. Blood samples were obtained by cardiac puncture. No mortality and clinical signs of toxicity were observed upon administration of HP for both acute and sub acute toxicity studies. Blood analysis showed significant changes in certain blood parameters. In the acute toxicity study, the blood levels of urea were significantly lower in the treatment group. In the sub acute toxicity study, there were no significance differences between both groups for all parameters. It can be concluded that the flesh's extract of HP can affect certain blood parameters and possibly has hepatoprotective effects. Further studies are needed to validate these effects in order to ensure the safe consumption of HP fruit.
format	Thesis
qualification_level	Bachelor degree
author	Darnalis, Nur Mardhiya
author_facet	Darnalis, Nur Mardhiya
author_sort	Darnalis, Nur Mardhiya
title	Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_short	Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_full	Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_fullStr	Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_full_unstemmed	Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis
title_sort	effects of hylocereus polyrhizus flesh on blood parameters in mice / nur mardhiya darnalis
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2007
url	https://ir.uitm.edu.my/id/eprint/100069/1/100069.PDF
_version_	1811769056377700352

Effects of hylocereus polyrhizus flesh on blood parameters in mice / Nur Mardhiya Darnalis

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