Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud

The present study was carried out with an intension to study the effect of the presence of the polyethylene glycol in water and also in presence and absence of one aqueous insoluble drug Griseofulvin in the former solution. Parameters used the volumetric parameters like density and one parameter rel...

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Main Author:	Daud, Shairah
Format:	Thesis
Language:	English
Published:	2008
Subjects:	RM Therapeutics Pharmacology RS Pharmacy and materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/101027/1/101027.PDF
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id	my-uitm-ir.101027
record_format	uketd_dc
spelling	my-uitm-ir.1010272024-08-26T04:29:01Z Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud 2008 Daud, Shairah RM Therapeutics. Pharmacology RS Pharmacy and materia medica The present study was carried out with an intension to study the effect of the presence of the polyethylene glycol in water and also in presence and absence of one aqueous insoluble drug Griseofulvin in the former solution. Parameters used the volumetric parameters like density and one parameter related to the surface is surface tension. It was observed that the parameters density showed an anomalous trend is a decrease in the density of water because of the presence of PEGs (PEG 1500, 4000 and 6000) up to a specific extent as the concentration were increased, but later at higher concentration the density was increased. In case of surface tension, the presence of PEGs reduced the surface tension. Where as in presence of Griseofulvin an increase in the decreased surface tension was observed. But when Griseofulvin was introduced alone, the surface tension of water was further increased indicating a further consolidation of the intermolecular force between water molecules. This study presented some valuable information regarding the interactions between the aqueous insoluble drug Griseofulvin and water and resultant change because of the presence of the solubility enhancer PEG 1500, 4000 and 6000 of course in a varied manner. 2008 Thesis https://ir.uitm.edu.my/id/eprint/101027/ https://ir.uitm.edu.my/id/eprint/101027/1/101027.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Tripathy, Minaketan
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Tripathy, Minaketan
topic	RM Therapeutics Pharmacology RS Pharmacy and materia medica
spellingShingle	RM Therapeutics Pharmacology RS Pharmacy and materia medica Daud, Shairah Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
description	The present study was carried out with an intension to study the effect of the presence of the polyethylene glycol in water and also in presence and absence of one aqueous insoluble drug Griseofulvin in the former solution. Parameters used the volumetric parameters like density and one parameter related to the surface is surface tension. It was observed that the parameters density showed an anomalous trend is a decrease in the density of water because of the presence of PEGs (PEG 1500, 4000 and 6000) up to a specific extent as the concentration were increased, but later at higher concentration the density was increased. In case of surface tension, the presence of PEGs reduced the surface tension. Where as in presence of Griseofulvin an increase in the decreased surface tension was observed. But when Griseofulvin was introduced alone, the surface tension of water was further increased indicating a further consolidation of the intermolecular force between water molecules. This study presented some valuable information regarding the interactions between the aqueous insoluble drug Griseofulvin and water and resultant change because of the presence of the solubility enhancer PEG 1500, 4000 and 6000 of course in a varied manner.
format	Thesis
qualification_level	Bachelor degree
author	Daud, Shairah
author_facet	Daud, Shairah
author_sort	Daud, Shairah
title	Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_short	Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_full	Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_fullStr	Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_full_unstemmed	Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_sort	investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / shairah daud
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2008
url	https://ir.uitm.edu.my/id/eprint/101027/1/101027.PDF
_version_	1811769120903921664

Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud

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