Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud

The present study was carried out with an intension to study the effect of the presence of the polyethylene glycol in water and also in presence and absence of one aqueous insoluble drug Griseofulvin in the former solution. Parameters used the volumetric parameters like density and one parameter rel...

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主要作者: Daud, Shairah
格式: Thesis
语言:English
出版: 2008
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spelling my-uitm-ir.1010272024-08-26T04:29:01Z Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud 2008 Daud, Shairah RM Therapeutics. Pharmacology RS Pharmacy and materia medica The present study was carried out with an intension to study the effect of the presence of the polyethylene glycol in water and also in presence and absence of one aqueous insoluble drug Griseofulvin in the former solution. Parameters used the volumetric parameters like density and one parameter related to the surface is surface tension. It was observed that the parameters density showed an anomalous trend is a decrease in the density of water because of the presence of PEGs (PEG 1500, 4000 and 6000) up to a specific extent as the concentration were increased, but later at higher concentration the density was increased. In case of surface tension, the presence of PEGs reduced the surface tension. Where as in presence of Griseofulvin an increase in the decreased surface tension was observed. But when Griseofulvin was introduced alone, the surface tension of water was further increased indicating a further consolidation of the intermolecular force between water molecules. This study presented some valuable information regarding the interactions between the aqueous insoluble drug Griseofulvin and water and resultant change because of the presence of the solubility enhancer PEG 1500, 4000 and 6000 of course in a varied manner. 2008 Thesis https://ir.uitm.edu.my/id/eprint/101027/ https://ir.uitm.edu.my/id/eprint/101027/1/101027.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Tripathy, Minaketan
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Tripathy, Minaketan
topic RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics
Pharmacology
RS Pharmacy and materia medica
Daud, Shairah
Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
description The present study was carried out with an intension to study the effect of the presence of the polyethylene glycol in water and also in presence and absence of one aqueous insoluble drug Griseofulvin in the former solution. Parameters used the volumetric parameters like density and one parameter related to the surface is surface tension. It was observed that the parameters density showed an anomalous trend is a decrease in the density of water because of the presence of PEGs (PEG 1500, 4000 and 6000) up to a specific extent as the concentration were increased, but later at higher concentration the density was increased. In case of surface tension, the presence of PEGs reduced the surface tension. Where as in presence of Griseofulvin an increase in the decreased surface tension was observed. But when Griseofulvin was introduced alone, the surface tension of water was further increased indicating a further consolidation of the intermolecular force between water molecules. This study presented some valuable information regarding the interactions between the aqueous insoluble drug Griseofulvin and water and resultant change because of the presence of the solubility enhancer PEG 1500, 4000 and 6000 of course in a varied manner.
format Thesis
qualification_level Bachelor degree
author Daud, Shairah
author_facet Daud, Shairah
author_sort Daud, Shairah
title Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_short Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_full Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_fullStr Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_full_unstemmed Investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / Shairah Daud
title_sort investigation on the density and surface tension of water in presence of griseofulvin and solubility enhancers / shairah daud
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2008
url https://ir.uitm.edu.my/id/eprint/101027/1/101027.PDF
_version_ 1811769120903921664