Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman

Malay traditional herbs have been widely used in both traditional as well as modern communities in Malaysia. These herbs have become a natural alternative for individuals who have strong beliefs in the safety and efficacy of traditional medicines. These traditional herbs are generally used in the tr...

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Main Author:	Othman, Hazlin
Format:	Thesis
Language:	English
Published:	2008
Subjects:	Pharmacognosy Pharmaceutical substances (Plant, animal, and inorganic)
Online Access:	https://ir.uitm.edu.my/id/eprint/101150/1/101150.PDF
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id	my-uitm-ir.101150
record_format	uketd_dc
spelling	my-uitm-ir.1011502024-09-28T23:35:19Z Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman 2008 Othman, Hazlin Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Malay traditional herbs have been widely used in both traditional as well as modern communities in Malaysia. These herbs have become a natural alternative for individuals who have strong beliefs in the safety and efficacy of traditional medicines. These traditional herbs are generally used in the treatment of certain medical conditions or even in maintenance of general health. Therefore, there is a need for a method development in profiling Malay traditional herbs. In this research, thin layer chromatography is applied as it is a fast technique used to determine separation of compounds in mixtures. The thin layer chromatography carried out in the research uses silica gel as the stationary phase and mixtures of solvent as the mobile phase. Different solvent systems comprising of hexane, ethyl acetate, chloroform, and methanol are used at different ratios to obtain the optimal separation of compounds. Optimization of solvent system has also been done to determine the best solvent system for each of the selected 12 herbs. Comparisons between herbals of same families have also been done. In addition, the presence of herbal extracts in a product is also determined through comparison of Rr values between the plant's extracts and product's extracts. Based on the Rr values, colours of the bands and fluorescence, results have shown that the similarities of the bands observed in hexane, chloroform and butanol extracts of the plant and products are 50.00 % , 66.67 %, and 41.18 % respectively. Thin layer chromatography has been found to be an effective, reliable, rapid and relatively inexpensive method in doing separations and identifications of compounds. 2008 Thesis https://ir.uitm.edu.my/id/eprint/101150/ https://ir.uitm.edu.my/id/eprint/101150/1/101150.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Yan, Choo Chee
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Yan, Choo Chee
topic	Pharmacognosy Pharmaceutical substances (Plant, animal, and inorganic)
spellingShingle	Pharmacognosy Pharmaceutical substances (Plant, animal, and inorganic) Othman, Hazlin Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman
description	Malay traditional herbs have been widely used in both traditional as well as modern communities in Malaysia. These herbs have become a natural alternative for individuals who have strong beliefs in the safety and efficacy of traditional medicines. These traditional herbs are generally used in the treatment of certain medical conditions or even in maintenance of general health. Therefore, there is a need for a method development in profiling Malay traditional herbs. In this research, thin layer chromatography is applied as it is a fast technique used to determine separation of compounds in mixtures. The thin layer chromatography carried out in the research uses silica gel as the stationary phase and mixtures of solvent as the mobile phase. Different solvent systems comprising of hexane, ethyl acetate, chloroform, and methanol are used at different ratios to obtain the optimal separation of compounds. Optimization of solvent system has also been done to determine the best solvent system for each of the selected 12 herbs. Comparisons between herbals of same families have also been done. In addition, the presence of herbal extracts in a product is also determined through comparison of Rr values between the plant's extracts and product's extracts. Based on the Rr values, colours of the bands and fluorescence, results have shown that the similarities of the bands observed in hexane, chloroform and butanol extracts of the plant and products are 50.00 % , 66.67 %, and 41.18 % respectively. Thin layer chromatography has been found to be an effective, reliable, rapid and relatively inexpensive method in doing separations and identifications of compounds.
format	Thesis
qualification_level	Bachelor degree
author	Othman, Hazlin
author_facet	Othman, Hazlin
author_sort	Othman, Hazlin
title	Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman
title_short	Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman
title_full	Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman
title_fullStr	Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman
title_full_unstemmed	Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman
title_sort	thin layer chromatography profiling of malay traditional herbs / hazlin othman
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2008
url	https://ir.uitm.edu.my/id/eprint/101150/1/101150.PDF
_version_	1811769135263121408

Thin layer chromatography profiling of Malay traditional herbs / Hazlin Othman

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