The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin

Synergistic effects of antioxidant and sunscreen agents have been intensively studied in recent years with regard of capability of UV radiation induced formation of reactive oxygen species (ROS). High level of ROS can lead to development of diseases such as heart diseases, malaria, neurodegenerative...

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Main Author:	Samsudin, Nurul Syazfeeza
Format:	Thesis
Language:	English
Published:	2008
Subjects:	Examination and analysis Composition Adulteration
Online Access:	https://ir.uitm.edu.my/id/eprint/101230/1/101230.PDF
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id	my-uitm-ir.101230
record_format	uketd_dc
spelling	my-uitm-ir.1012302024-09-28T23:38:18Z The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin 2008 Samsudin, Nurul Syazfeeza Examination and analysis. Composition. Adulteration Synergistic effects of antioxidant and sunscreen agents have been intensively studied in recent years with regard of capability of UV radiation induced formation of reactive oxygen species (ROS). High level of ROS can lead to development of diseases such as heart diseases, malaria, neurodegenerative diseases, AIDS, cancer and in the aging process. Antioxidants are substances that can prevent and repair the damage done by the ROS. This study had investigated the antioxidant activity and the in vitro sun protection factor (SPF) of Cassia alata leaves extract in a gel formulation. 2,2-diphenyl-1- picrylhydrazyl radical (DPPH) method was used to determine the antioxidant activity of methanol (CAME) and aqueous extract (CAAE) of C. alata. The sun protection factor was analyzed by using the diffuse transmittance method. Both extracts showed moderate antioxidant activity where CAME and CAAE need 31.62 µg/mL and 100 µg/mL respectively to achieve 50 % effective concentration (EC50). In SPF assay, CAAE and CAME of C. alata had the highest SPFs, i.e. 4.71 and 2.54, respectively at concentration 10 µg/mL. 2008 Thesis https://ir.uitm.edu.my/id/eprint/101230/ https://ir.uitm.edu.my/id/eprint/101230/1/101230.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Dianita, Roza
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Dianita, Roza
topic	Examination and analysis Composition Adulteration
spellingShingle	Examination and analysis Composition Adulteration Samsudin, Nurul Syazfeeza The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin
description	Synergistic effects of antioxidant and sunscreen agents have been intensively studied in recent years with regard of capability of UV radiation induced formation of reactive oxygen species (ROS). High level of ROS can lead to development of diseases such as heart diseases, malaria, neurodegenerative diseases, AIDS, cancer and in the aging process. Antioxidants are substances that can prevent and repair the damage done by the ROS. This study had investigated the antioxidant activity and the in vitro sun protection factor (SPF) of Cassia alata leaves extract in a gel formulation. 2,2-diphenyl-1- picrylhydrazyl radical (DPPH) method was used to determine the antioxidant activity of methanol (CAME) and aqueous extract (CAAE) of C. alata. The sun protection factor was analyzed by using the diffuse transmittance method. Both extracts showed moderate antioxidant activity where CAME and CAAE need 31.62 µg/mL and 100 µg/mL respectively to achieve 50 % effective concentration (EC50). In SPF assay, CAAE and CAME of C. alata had the highest SPFs, i.e. 4.71 and 2.54, respectively at concentration 10 µg/mL.
format	Thesis
qualification_level	Bachelor degree
author	Samsudin, Nurul Syazfeeza
author_facet	Samsudin, Nurul Syazfeeza
author_sort	Samsudin, Nurul Syazfeeza
title	The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin
title_short	The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin
title_full	The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin
title_fullStr	The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin
title_full_unstemmed	The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin
title_sort	study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / nurul syazfeeza samsudin
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2008
url	https://ir.uitm.edu.my/id/eprint/101230/1/101230.PDF
_version_	1811769150719131648

The study of antioxidant and sun protection properties of cassia alata leaves (galenggang) / Nurul Syazfeeza Samsudin

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