Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman

Antioxidants are substances that can fight and destroy excess free radicals and repair oxidative damage. Incorporation of antioxidant into a sunscreen may enhance its sun protection factor and at the same time provide protection from free radicals damage. The antioxidant activities of Curcuma xantho...

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Main Author: Mohd Saman, Norahsikin
Format: Thesis
Language:English
Published: 2008
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/102038/1/102038.PDF
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spelling my-uitm-ir.1020382024-09-11T19:20:48Z Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman 2008 Mohd Saman, Norahsikin Pharmaceutical technology Pharmaceutical chemistry Antioxidants are substances that can fight and destroy excess free radicals and repair oxidative damage. Incorporation of antioxidant into a sunscreen may enhance its sun protection factor and at the same time provide protection from free radicals damage. The antioxidant activities of Curcuma xanthorrhiza aqueous and methanolic extract had been investigated by using I, l-diphenyl-2-picrylhydrazyl (DPPH) assay. Determination of the sun protection factor was carried out by using diffuse transmittance measurements. CXME exhibit greater radical scavenging activity than CXAE. In the DPPH assay, CXAE require 95.50 µg/mL to achieve 50% effective concentration while CXME require 33.50 µg/mL. The SPF value of C xanthorrhiza measured in four different concentration is directly proportional to its concentration. CXME exhibit higher SPF value which is 3.74 compared to CXAE whicH is 2.64 at concentration I 0%. These results suggest that C xanthorrhiza could be a good source of natural antioxidant but some modification may be done to improve its SPF value for cosmeceutical product. 2008 Thesis https://ir.uitm.edu.my/id/eprint/102038/ https://ir.uitm.edu.my/id/eprint/102038/1/102038.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
topic Pharmaceutical technology
Pharmaceutical chemistry
spellingShingle Pharmaceutical technology
Pharmaceutical chemistry
Mohd Saman, Norahsikin
Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman
description Antioxidants are substances that can fight and destroy excess free radicals and repair oxidative damage. Incorporation of antioxidant into a sunscreen may enhance its sun protection factor and at the same time provide protection from free radicals damage. The antioxidant activities of Curcuma xanthorrhiza aqueous and methanolic extract had been investigated by using I, l-diphenyl-2-picrylhydrazyl (DPPH) assay. Determination of the sun protection factor was carried out by using diffuse transmittance measurements. CXME exhibit greater radical scavenging activity than CXAE. In the DPPH assay, CXAE require 95.50 µg/mL to achieve 50% effective concentration while CXME require 33.50 µg/mL. The SPF value of C xanthorrhiza measured in four different concentration is directly proportional to its concentration. CXME exhibit higher SPF value which is 3.74 compared to CXAE whicH is 2.64 at concentration I 0%. These results suggest that C xanthorrhiza could be a good source of natural antioxidant but some modification may be done to improve its SPF value for cosmeceutical product.
format Thesis
qualification_level Bachelor degree
author Mohd Saman, Norahsikin
author_facet Mohd Saman, Norahsikin
author_sort Mohd Saman, Norahsikin
title Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman
title_short Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman
title_full Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman
title_fullStr Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman
title_full_unstemmed Determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / Norahsikin Mohd Saman
title_sort determination of antioxidant and sun protection factor of plant curcuma xanthorrhiza (temulawak) / norahsikin mohd saman
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2008
url https://ir.uitm.edu.my/id/eprint/102038/1/102038.PDF
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