Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad
The focus of this study was to synthesize naphthoquinone derivatives, 49 via pyridinium salt of phenacyl bromide, 48 and also study on percentage rate of formation for pyridinium salt. Phenacyl bromide and pyridine were refluxed for five days to formed pyridinium salt, 48. The percentage yield of py...
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2010
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| Online Access: | https://ir.uitm.edu.my/id/eprint/103085/1/103085.pdf |
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my-uitm-ir.1030852024-09-28T16:01:09Z Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad 2010 Muhamad, Nor Zaimah The focus of this study was to synthesize naphthoquinone derivatives, 49 via pyridinium salt of phenacyl bromide, 48 and also study on percentage rate of formation for pyridinium salt. Phenacyl bromide and pyridine were refluxed for five days to formed pyridinium salt, 48. The percentage yield of pyridinium salt obtained was 99.3%. The salt, 48 then reacted with 2-methyl-1,4-naphthoquinone, 8 by stirring overnight. Then, followed by filtration, extraction of solvent, recrystallization and lastly the product obtained separated by column chromatography to separate the optical isomers which were yellow and red. The percentage yields of products, 49 were 49.5% in form of mixture yellow and red isomers. Then, the two isomers were analyse with NMR, FTIR, and melting point analysis. 2010 Thesis https://ir.uitm.edu.my/id/eprint/103085/ https://ir.uitm.edu.my/id/eprint/103085/1/103085.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Applied Sciences Abdul Ghani, Fazni Susila |
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Universiti Teknologi MARA |
| collection |
UiTM Institutional Repository |
| language |
English |
| advisor |
Abdul Ghani, Fazni Susila |
| description |
The focus of this study was to synthesize naphthoquinone derivatives, 49 via pyridinium salt of phenacyl bromide, 48 and also study on percentage rate of formation for pyridinium salt. Phenacyl bromide and pyridine were refluxed for five days to formed pyridinium salt, 48. The percentage yield of pyridinium salt obtained was 99.3%. The salt, 48 then reacted with 2-methyl-1,4-naphthoquinone, 8 by stirring overnight. Then, followed by filtration, extraction of solvent, recrystallization and lastly the product obtained separated by column chromatography to separate the optical isomers which were yellow and red. The percentage yields of products, 49 were 49.5% in form of mixture yellow and red isomers. Then, the two isomers were analyse with NMR, FTIR, and melting point analysis. |
| format |
Thesis |
| qualification_level |
Bachelor degree |
| author |
Muhamad, Nor Zaimah |
| spellingShingle |
Muhamad, Nor Zaimah Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad |
| author_facet |
Muhamad, Nor Zaimah |
| author_sort |
Muhamad, Nor Zaimah |
| title |
Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad |
| title_short |
Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad |
| title_full |
Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad |
| title_fullStr |
Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad |
| title_full_unstemmed |
Synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / Nor Zaimah Muhamad |
| title_sort |
synthesis of naphthoquinone derivatives with some study on percentage rate of formation for pyridinium salt / nor zaimah muhamad |
| granting_institution |
Universiti Teknologi MARA (UiTM) |
| granting_department |
Faculty of Applied Sciences |
| publishDate |
2010 |
| url |
https://ir.uitm.edu.my/id/eprint/103085/1/103085.pdf |
| _version_ |
1811769244689367040 |