Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin

Recent laboratory and clinical studies suggest that Diabetes Mellitus induce alterations in neuroendocrine system may bring about pathophysiological changes that negatively affect sexual function of female WKY rats. However, these studies have been few in number and are limited in scope. We analyzed...

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Main Author:	Russin, Siti Fatimar
Format:	Thesis
Language:	English
Published:	2008
Subjects:	Diabetes Mellitus
Online Access:	https://ir.uitm.edu.my/id/eprint/103914/1/103914.PDF
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id	my-uitm-ir.103914
record_format	uketd_dc
spelling	my-uitm-ir.1039142024-09-28T23:38:14Z Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin 2008 Russin, Siti Fatimar Diabetes Mellitus Recent laboratory and clinical studies suggest that Diabetes Mellitus induce alterations in neuroendocrine system may bring about pathophysiological changes that negatively affect sexual function of female WKY rats. However, these studies have been few in number and are limited in scope. We analyzed the effect of STZ induced diabetes on estrus cycle of female WKY rats. Diabetes significantly altered female reproductive cycle and level of reproductive hormone. Diabetes led to persistent diestrus, supported by decreased in levels of estrogen and luteinizing hormone, and increased in progesterone level. Diabetes alteration of female WKY may be due to failure of insulin metabolism and impaired insulin aromatase crosstalk. 2008 Thesis https://ir.uitm.edu.my/id/eprint/103914/ https://ir.uitm.edu.my/id/eprint/103914/1/103914.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Igueebe, Aloysius Umelo
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Igueebe, Aloysius Umelo
topic	Diabetes Mellitus
spellingShingle	Diabetes Mellitus Russin, Siti Fatimar Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin
description	Recent laboratory and clinical studies suggest that Diabetes Mellitus induce alterations in neuroendocrine system may bring about pathophysiological changes that negatively affect sexual function of female WKY rats. However, these studies have been few in number and are limited in scope. We analyzed the effect of STZ induced diabetes on estrus cycle of female WKY rats. Diabetes significantly altered female reproductive cycle and level of reproductive hormone. Diabetes led to persistent diestrus, supported by decreased in levels of estrogen and luteinizing hormone, and increased in progesterone level. Diabetes alteration of female WKY may be due to failure of insulin metabolism and impaired insulin aromatase crosstalk.
format	Thesis
qualification_level	Bachelor degree
author	Russin, Siti Fatimar
author_facet	Russin, Siti Fatimar
author_sort	Russin, Siti Fatimar
title	Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin
title_short	Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin
title_full	Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin
title_fullStr	Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin
title_full_unstemmed	Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin
title_sort	effects of diabetes mellitus on estrous cycle of wky rat / siti fatimar russin
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2008
url	https://ir.uitm.edu.my/id/eprint/103914/1/103914.PDF
_version_	1811769271462658048

Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin

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