Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin
Recent laboratory and clinical studies suggest that Diabetes Mellitus induce alterations in neuroendocrine system may bring about pathophysiological changes that negatively affect sexual function of female WKY rats. However, these studies have been few in number and are limited in scope. We analyzed...
محفوظ في:
| المؤلف الرئيسي: | |
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| التنسيق: | أطروحة |
| اللغة: | English |
| منشور في: |
2008
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ir.uitm.edu.my/id/eprint/103914/1/103914.PDF |
| الوسوم: |
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my-uitm-ir.103914 |
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uketd_dc |
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my-uitm-ir.1039142024-09-28T23:38:14Z Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin 2008 Russin, Siti Fatimar Diabetes Mellitus Recent laboratory and clinical studies suggest that Diabetes Mellitus induce alterations in neuroendocrine system may bring about pathophysiological changes that negatively affect sexual function of female WKY rats. However, these studies have been few in number and are limited in scope. We analyzed the effect of STZ induced diabetes on estrus cycle of female WKY rats. Diabetes significantly altered female reproductive cycle and level of reproductive hormone. Diabetes led to persistent diestrus, supported by decreased in levels of estrogen and luteinizing hormone, and increased in progesterone level. Diabetes alteration of female WKY may be due to failure of insulin metabolism and impaired insulin aromatase crosstalk. 2008 Thesis https://ir.uitm.edu.my/id/eprint/103914/ https://ir.uitm.edu.my/id/eprint/103914/1/103914.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Igueebe, Aloysius Umelo |
| institution |
Universiti Teknologi MARA |
| collection |
UiTM Institutional Repository |
| language |
English |
| advisor |
Igueebe, Aloysius Umelo |
| topic |
Diabetes Mellitus |
| spellingShingle |
Diabetes Mellitus Russin, Siti Fatimar Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin |
| description |
Recent laboratory and clinical studies suggest that Diabetes Mellitus induce alterations in neuroendocrine system may bring about pathophysiological changes that negatively affect sexual function of female WKY rats. However, these studies have been few in number and are limited in scope. We analyzed the effect of STZ induced diabetes on estrus cycle of female WKY rats. Diabetes significantly altered female reproductive cycle and level of reproductive hormone. Diabetes led to persistent diestrus, supported by decreased in levels of estrogen and luteinizing hormone, and increased in progesterone level. Diabetes alteration of female WKY may be due to failure of insulin metabolism and impaired insulin aromatase crosstalk. |
| format |
Thesis |
| qualification_level |
Bachelor degree |
| author |
Russin, Siti Fatimar |
| author_facet |
Russin, Siti Fatimar |
| author_sort |
Russin, Siti Fatimar |
| title |
Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin |
| title_short |
Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin |
| title_full |
Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin |
| title_fullStr |
Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin |
| title_full_unstemmed |
Effects of diabetes mellitus on estrous cycle of wky rat / Siti Fatimar Russin |
| title_sort |
effects of diabetes mellitus on estrous cycle of wky rat / siti fatimar russin |
| granting_institution |
Universiti Teknologi MARA (Kampus Puncak Alam) |
| granting_department |
Faculty of Pharmacy |
| publishDate |
2008 |
| url |
https://ir.uitm.edu.my/id/eprint/103914/1/103914.PDF |
| _version_ |
1811769271462658048 |