Cloning and transformation of human multidrug resistance gene 1 (MDR1) / Hamidah Mokhtaruddin
Human MDR1 encoded for P-glycoprotein (P-gp) formation. P-gp is an ATP dependent efflux transporter which reduces the intracellular concentration of wide range of drugs including the chemotherapy drugs especially when the MDR1 gene being over expressed. Most of the anticancer agents are the substrat...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/105121/1/105121.PDF |
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