Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim

Turmeric, Curcuma longa L. (Zingiberaceae), has been attributed to a number of medicinal properties in the traditional system of medicine for treating several common ailments. I want to investigate the anti-inflammatory effect of Turmeric in rats with carrageenan-induced paw edema and alterations in...

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Main Author: Ibrahim, Iylia Nur Diyana
Format: Thesis
Language:English
Published: 2009
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Online Access:https://ir.uitm.edu.my/id/eprint/105208/1/105208.PDF
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spelling my-uitm-ir.1052082024-12-05T09:06:56Z Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim 2009 Ibrahim, Iylia Nur Diyana Pharmaceutical chemistry Turmeric, Curcuma longa L. (Zingiberaceae), has been attributed to a number of medicinal properties in the traditional system of medicine for treating several common ailments. I want to investigate the anti-inflammatory effect of Turmeric in rats with carrageenan-induced paw edema and alterations in the glutathione (GSH) level and the activities of antioxidative enzymes (superoxide dismutase, catalase, and glutathione reductase), as marker of acute inflammation, following oral administration of Turmeric and Acetyl Salicylic Acid (ASA) in rats with carrageenan-induced paw edema. In the previous studies, the researchers found that 1) Turmeric reduced the development of carrageenan-induced paw edema, to a greater degree than ASA; 2) Turmeric and ASA alleviated increases in the activities of catalase enzyme resulting from edema caused by carrageenan injection. These results suggest that the anti-inflammatory effect of Turmeric on carrageenan-induced acute inflammation can be attributed to its ameliorating effect on the oxidative damage. 2009 Thesis https://ir.uitm.edu.my/id/eprint/105208/ https://ir.uitm.edu.my/id/eprint/105208/1/105208.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Adam, Aishah
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Adam, Aishah
topic Pharmaceutical chemistry
spellingShingle Pharmaceutical chemistry
Ibrahim, Iylia Nur Diyana
Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim
description Turmeric, Curcuma longa L. (Zingiberaceae), has been attributed to a number of medicinal properties in the traditional system of medicine for treating several common ailments. I want to investigate the anti-inflammatory effect of Turmeric in rats with carrageenan-induced paw edema and alterations in the glutathione (GSH) level and the activities of antioxidative enzymes (superoxide dismutase, catalase, and glutathione reductase), as marker of acute inflammation, following oral administration of Turmeric and Acetyl Salicylic Acid (ASA) in rats with carrageenan-induced paw edema. In the previous studies, the researchers found that 1) Turmeric reduced the development of carrageenan-induced paw edema, to a greater degree than ASA; 2) Turmeric and ASA alleviated increases in the activities of catalase enzyme resulting from edema caused by carrageenan injection. These results suggest that the anti-inflammatory effect of Turmeric on carrageenan-induced acute inflammation can be attributed to its ameliorating effect on the oxidative damage.
format Thesis
qualification_level Bachelor degree
author Ibrahim, Iylia Nur Diyana
author_facet Ibrahim, Iylia Nur Diyana
author_sort Ibrahim, Iylia Nur Diyana
title Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim
title_short Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim
title_full Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim
title_fullStr Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim
title_full_unstemmed Antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / Iylia Nur Diyana Ibrahim
title_sort antioxidant and anti-inflammatory activities of curcuma longa in an experimental study in rats with carrageenan-induced paw edema / iylia nur diyana ibrahim
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2009
url https://ir.uitm.edu.my/id/eprint/105208/1/105208.PDF
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