Chromatographic study of vitex methanol extract / Fia Iskandar

The methanolic extract of the leaves of Vitex trifolia was fractionated in order to obtain relatively polar compounds. Two compounds namely Compound A and Compound B were isolated and purified. They were subjected under 1H-NMR spectroscopy. The 1H-NMR spectrum of the compounds were analysed and comp...

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Main Author: Iskandar, Fia
Format: Thesis
Language:English
Published: 2009
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Online Access:https://ir.uitm.edu.my/id/eprint/105346/1/105346.PDF
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spelling my-uitm-ir.1053462024-12-05T08:54:07Z Chromatographic study of vitex methanol extract / Fia Iskandar 2009 Iskandar, Fia Pharmaceutical industry The methanolic extract of the leaves of Vitex trifolia was fractionated in order to obtain relatively polar compounds. Two compounds namely Compound A and Compound B were isolated and purified. They were subjected under 1H-NMR spectroscopy. The 1H-NMR spectrum of the compounds were analysed and compared with the findings from other journals. Compound A was suggested to have a methoxy, a phenol, a hydroxyl, a carboxylic, and an aromatic proton. Meanwhile, compound B may possess methoxy or carboxylic groups. Hydroxyl and carboxylic groups contributes to the polar characteristic of the compound. In addition, the literature review showed that the highly polar extracts of Vitex species have been found to be cytotoxic. 2009 Thesis https://ir.uitm.edu.my/id/eprint/105346/ https://ir.uitm.edu.my/id/eprint/105346/1/105346.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Abdul Wahab, lbtisam
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Abdul Wahab, lbtisam
topic Pharmaceutical industry
spellingShingle Pharmaceutical industry
Iskandar, Fia
Chromatographic study of vitex methanol extract / Fia Iskandar
description The methanolic extract of the leaves of Vitex trifolia was fractionated in order to obtain relatively polar compounds. Two compounds namely Compound A and Compound B were isolated and purified. They were subjected under 1H-NMR spectroscopy. The 1H-NMR spectrum of the compounds were analysed and compared with the findings from other journals. Compound A was suggested to have a methoxy, a phenol, a hydroxyl, a carboxylic, and an aromatic proton. Meanwhile, compound B may possess methoxy or carboxylic groups. Hydroxyl and carboxylic groups contributes to the polar characteristic of the compound. In addition, the literature review showed that the highly polar extracts of Vitex species have been found to be cytotoxic.
format Thesis
qualification_level Bachelor degree
author Iskandar, Fia
author_facet Iskandar, Fia
author_sort Iskandar, Fia
title Chromatographic study of vitex methanol extract / Fia Iskandar
title_short Chromatographic study of vitex methanol extract / Fia Iskandar
title_full Chromatographic study of vitex methanol extract / Fia Iskandar
title_fullStr Chromatographic study of vitex methanol extract / Fia Iskandar
title_full_unstemmed Chromatographic study of vitex methanol extract / Fia Iskandar
title_sort chromatographic study of vitex methanol extract / fia iskandar
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2009
url https://ir.uitm.edu.my/id/eprint/105346/1/105346.PDF
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