Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at

The aim of this study is to optimize the virgin coconut oil in formulation of nano-emulsion. In this study we prepare various formulations of emulsion consist of virgin coconut oil as disperse phase. From the formulations we prepare, we investigate the influences of Tween 80 as surfactant and Span 8...

Full description

Saved in:
Bibliographic Details
Main Author: Sarl'at, Muhd Bahrudin
Format: Thesis
Language:English
Published: 2009
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/107027/1/107027.PDF
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-uitm-ir.107027
record_format uketd_dc
spelling my-uitm-ir.1070272024-12-10T23:13:09Z Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at 2009 Sarl'at, Muhd Bahrudin Pharmaceutical industry Pharmaceutical chemistry The aim of this study is to optimize the virgin coconut oil in formulation of nano-emulsion. In this study we prepare various formulations of emulsion consist of virgin coconut oil as disperse phase. From the formulations we prepare, we investigate the influences of Tween 80 as surfactant and Span 80 as co-surfactant in term of make the virgin coconut oil emulsion in nano range of size droplet. The result shows in ratio of 2: 1 between virgin coconut oil and surfactant and ration 2: I also between Tween 80 and Span 80 give us the smallest mean droplet size which is 0.1 86 µm. Moreover, we also investigate the nano-emulsion produced stability which we leave the nano-emulsion for one week in laboratory and measure the size particle again after that. The result was not significance change from 0.186 µm to 0.194 µm. As the conclusion, this research is really beneficial to optimize and find out the best possible formulation and production of the Virgin Coconut Oil nano-emulsion by self-emulsifying agent. 2009 Thesis https://ir.uitm.edu.my/id/eprint/107027/ https://ir.uitm.edu.my/id/eprint/107027/1/107027.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Mustafa Eid, Ahmad
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Mustafa Eid, Ahmad
topic Pharmaceutical industry
Pharmaceutical chemistry
spellingShingle Pharmaceutical industry
Pharmaceutical chemistry
Sarl'at, Muhd Bahrudin
Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at
description The aim of this study is to optimize the virgin coconut oil in formulation of nano-emulsion. In this study we prepare various formulations of emulsion consist of virgin coconut oil as disperse phase. From the formulations we prepare, we investigate the influences of Tween 80 as surfactant and Span 80 as co-surfactant in term of make the virgin coconut oil emulsion in nano range of size droplet. The result shows in ratio of 2: 1 between virgin coconut oil and surfactant and ration 2: I also between Tween 80 and Span 80 give us the smallest mean droplet size which is 0.1 86 µm. Moreover, we also investigate the nano-emulsion produced stability which we leave the nano-emulsion for one week in laboratory and measure the size particle again after that. The result was not significance change from 0.186 µm to 0.194 µm. As the conclusion, this research is really beneficial to optimize and find out the best possible formulation and production of the Virgin Coconut Oil nano-emulsion by self-emulsifying agent.
format Thesis
qualification_level Bachelor degree
author Sarl'at, Muhd Bahrudin
author_facet Sarl'at, Muhd Bahrudin
author_sort Sarl'at, Muhd Bahrudin
title Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at
title_short Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at
title_full Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at
title_fullStr Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at
title_full_unstemmed Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sarl'at
title_sort formulation and optimization of medium-chain fatty acid nano-emulsion / muhd bahrudin sarl'at
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2009
url https://ir.uitm.edu.my/id/eprint/107027/1/107027.PDF
_version_ 1818588200841510912