Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin
This is a preliminary study which aim to observe the antihepatotoxic acnvity of Clidermia hirta. The aqueous extract of Clidermia hirta leave was evaluated for its toxicity and antihepatotoxic activity against acetaminophen-induced hepatotoxic in mice. Mice were given dose of extract 2500 mg/kg, lOO...
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| Language: | English |
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2009
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| Online Access: | https://ir.uitm.edu.my/id/eprint/107030/1/107030.PDF |
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my-uitm-ir.1070302024-12-10T23:07:37Z Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin 2009 Izaddin, Izana Nabilla Pharmaceutical industry Pharmaceutical chemistry This is a preliminary study which aim to observe the antihepatotoxic acnvity of Clidermia hirta. The aqueous extract of Clidermia hirta leave was evaluated for its toxicity and antihepatotoxic activity against acetaminophen-induced hepatotoxic in mice. Mice were given dose of extract 2500 mg/kg, lOOO mg/kg and 500mg/kg to determine the mortality rate which are I 00 %, 0 % and 0% respectively. Study is continued with antihepatotoxic study with 3 groups that consists of 6 mice each group. The groups are control (water+ acetaminophen) and 2 test (extract + acetaminophen) group which have 2 different extract dose. I 00 mg/kg and 50 mg/kg. The activity of the mice is evaluated by liver weight in gram per IO gram of bodyweight which is not so reliable to conclude any remarkable antihepatotoxic activity of this plant. 2009 Thesis https://ir.uitm.edu.my/id/eprint/107030/ https://ir.uitm.edu.my/id/eprint/107030/1/107030.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Meor Mohd Affandi, Meor Mohd Redzuan |
| institution |
Universiti Teknologi MARA |
| collection |
UiTM Institutional Repository |
| language |
English |
| advisor |
Meor Mohd Affandi, Meor Mohd Redzuan |
| topic |
Pharmaceutical industry Pharmaceutical chemistry |
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Pharmaceutical industry Pharmaceutical chemistry Izaddin, Izana Nabilla Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin |
| description |
This is a preliminary study which aim to observe the antihepatotoxic acnvity of Clidermia hirta. The aqueous extract of Clidermia hirta leave was evaluated for its toxicity and antihepatotoxic activity against acetaminophen-induced hepatotoxic in mice. Mice were given dose of extract 2500 mg/kg, lOOO mg/kg and 500mg/kg to determine the mortality rate which are I 00 %, 0 % and 0% respectively. Study is continued with antihepatotoxic study with 3 groups that consists of 6 mice each group. The groups are control (water+ acetaminophen) and 2 test (extract + acetaminophen) group which have 2 different extract dose. I 00 mg/kg and 50 mg/kg. The activity of the mice is evaluated by liver weight in gram per IO gram of bodyweight which is not so reliable to conclude any remarkable antihepatotoxic activity of this plant. |
| format |
Thesis |
| qualification_level |
Bachelor degree |
| author |
Izaddin, Izana Nabilla |
| author_facet |
Izaddin, Izana Nabilla |
| author_sort |
Izaddin, Izana Nabilla |
| title |
Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin |
| title_short |
Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin |
| title_full |
Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin |
| title_fullStr |
Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin |
| title_full_unstemmed |
Antihepatotoxicity of clidermia hirta / Izana Nabilla Izaddin |
| title_sort |
antihepatotoxicity of clidermia hirta / izana nabilla izaddin |
| granting_institution |
Universiti Teknologi MARA (Kampus Puncak Alam) |
| granting_department |
Faculty of Pharmacy |
| publishDate |
2009 |
| url |
https://ir.uitm.edu.my/id/eprint/107030/1/107030.PDF |
| _version_ |
1818588201590194176 |