Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at

The aim of this study is to optimize the virgin coconut oil in formulation of nano-emulsion. In this study we prepare various formulations of emulsion consist of virgin coconut oil as disperse phase. From the formulations we prepare, we investigate the influences of Tween 80 as surfactant and Span 8...

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Main Author:	Sari'at, Muhd Bahrudin
Format:	Thesis
Language:	English
Published:	2009
Subjects:	Pharmaceutical industry Pharmaceutical chemistry
Online Access:	https://ir.uitm.edu.my/id/eprint/107163/1/107163.PDF
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id	my-uitm-ir.107163
record_format	uketd_dc
spelling	my-uitm-ir.1071632024-12-10T23:13:05Z Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at 2009 Sari'at, Muhd Bahrudin Pharmaceutical industry Pharmaceutical chemistry The aim of this study is to optimize the virgin coconut oil in formulation of nano-emulsion. In this study we prepare various formulations of emulsion consist of virgin coconut oil as disperse phase. From the formulations we prepare, we investigate the influences of Tween 80 as surfactant and Span 80 as co-surfactant in term of make the virgin coconut oil emulsion in nano range of size droplet. The result shows in ratio of 2:1 between virgin coconut oil and surfactant and ration 2:1 also between Tween 80 and Span 80 give us the smallest mean droplet size which is 0.186 µm. Moreover, we also investigate the nano-emulsion produced stability which we leave the nano-emulsion for one week in laboratory and measure the size particle again after that. The result was not significance change from 0.186 µm to 0.194 µm. As the conclusion, this research is really beneficial to optimize and find out the best possible formulation and production of the Virgin Coconut Oil nano-emulsion by self-emulsifying agent. 2009 Thesis https://ir.uitm.edu.my/id/eprint/107163/ https://ir.uitm.edu.my/id/eprint/107163/1/107163.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Eid, Ahmad Mustafa
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Eid, Ahmad Mustafa
topic	Pharmaceutical industry Pharmaceutical chemistry
spellingShingle	Pharmaceutical industry Pharmaceutical chemistry Sari'at, Muhd Bahrudin Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at
description	The aim of this study is to optimize the virgin coconut oil in formulation of nano-emulsion. In this study we prepare various formulations of emulsion consist of virgin coconut oil as disperse phase. From the formulations we prepare, we investigate the influences of Tween 80 as surfactant and Span 80 as co-surfactant in term of make the virgin coconut oil emulsion in nano range of size droplet. The result shows in ratio of 2:1 between virgin coconut oil and surfactant and ration 2:1 also between Tween 80 and Span 80 give us the smallest mean droplet size which is 0.186 µm. Moreover, we also investigate the nano-emulsion produced stability which we leave the nano-emulsion for one week in laboratory and measure the size particle again after that. The result was not significance change from 0.186 µm to 0.194 µm. As the conclusion, this research is really beneficial to optimize and find out the best possible formulation and production of the Virgin Coconut Oil nano-emulsion by self-emulsifying agent.
format	Thesis
qualification_level	Bachelor degree
author	Sari'at, Muhd Bahrudin
author_facet	Sari'at, Muhd Bahrudin
author_sort	Sari'at, Muhd Bahrudin
title	Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at
title_short	Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at
title_full	Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at
title_fullStr	Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at
title_full_unstemmed	Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at
title_sort	formulation and optimization of medium-chain fatty acid nano-emulsion / muhd bahrudin sari'at
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2009
url	https://ir.uitm.edu.my/id/eprint/107163/1/107163.PDF
_version_	1818588210417106944

Formulation and optimization of medium-chain fatty acid nano-emulsion / Muhd Bahrudin Sari'at

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