Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi

Globally, the issue of Multidrug Resistant Tuberculosis (MDR-TB) was acknowledged as a threat to the successful prevention and treatment of TB. In Malaysia, TB remains a major health issue and incidence has been rising slowly for the past decade indicating poor success rate in current TB control pr...

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Main Author:	Azmi, Alia
Format:	Thesis
Language:	English
Published:	2013
Subjects:	Building fittings and their installation Building control systems
Online Access:	https://ir.uitm.edu.my/id/eprint/15474/1/TM_ALIA%20AZMI%20HS%2013_5.PDF
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id	my-uitm-ir.15474
record_format	uketd_dc
spelling	my-uitm-ir.154742022-02-28T00:54:43Z Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi 2013 Azmi, Alia Building fittings and their installation Building control systems Globally, the issue of Multidrug Resistant Tuberculosis (MDR-TB) was acknowledged as a threat to the successful prevention and treatment of TB. In Malaysia, TB remains a major health issue and incidence has been rising slowly for the past decade indicating poor success rate in current TB control programme. Currently, very little epidemiological data can be found regarding the situation of TB and MDR-TB in Malaysia. Therefore, this study aims to bridge the gap in information regarding TB and MDR-TB by identifying the population at risk. The objective of this study is also to identify the independent risk factors associated with MDR-TB in Malaysia. 477 TB patients from the Institute of Respiratory Medicine (IPR) were universally sampled based on the records of patients in 2010. Among 477 patients sampled, 67.9% were male with mean age 37.2 (SD 14.9). 30% of patients were foreign born with the majority were from Myanmar (14.9%), Indonesia (9.4%) and Bangladesh (2.7%). Prevalence of TB/HIV and TB/Diabetes among the patients sampled was 0.059 and 0.155 respectively. In multivariate analysis, BCG Status (AOR=0.292, 95%CI 0.13-0.67) was found to be a protective risk factor while history of previous TB (AOR=4.36, 95%CI 1.80-10.56) was a risk factor for MDR-TB.Whilst history of previous TB is a commonly acknowledged risk factor, the evidence of BCG as a protective factor for MDR-TB indicates that BCG vaccination is still a viable preventive measure. Association was found between BCG Status and foreign bom patients (p-value <0.01) indicating a need for active screening of immigrants. 2013 Thesis https://ir.uitm.edu.my/id/eprint/15474/ https://ir.uitm.edu.my/id/eprint/15474/1/TM_ALIA%20AZMI%20HS%2013_5.PDF text en public mphil masters Universiti Teknologi MARA Faculty of Architecture, Planning and Surveying
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Building fittings and their installation Building control systems
spellingShingle	Building fittings and their installation Building control systems Azmi, Alia Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
description	Globally, the issue of Multidrug Resistant Tuberculosis (MDR-TB) was acknowledged as a threat to the successful prevention and treatment of TB. In Malaysia, TB remains a major health issue and incidence has been rising slowly for the past decade indicating poor success rate in current TB control programme. Currently, very little epidemiological data can be found regarding the situation of TB and MDR-TB in Malaysia. Therefore, this study aims to bridge the gap in information regarding TB and MDR-TB by identifying the population at risk. The objective of this study is also to identify the independent risk factors associated with MDR-TB in Malaysia. 477 TB patients from the Institute of Respiratory Medicine (IPR) were universally sampled based on the records of patients in 2010. Among 477 patients sampled, 67.9% were male with mean age 37.2 (SD 14.9). 30% of patients were foreign born with the majority were from Myanmar (14.9%), Indonesia (9.4%) and Bangladesh (2.7%). Prevalence of TB/HIV and TB/Diabetes among the patients sampled was 0.059 and 0.155 respectively. In multivariate analysis, BCG Status (AOR=0.292, 95%CI 0.13-0.67) was found to be a protective risk factor while history of previous TB (AOR=4.36, 95%CI 1.80-10.56) was a risk factor for MDR-TB.Whilst history of previous TB is a commonly acknowledged risk factor, the evidence of BCG as a protective factor for MDR-TB indicates that BCG vaccination is still a viable preventive measure. Association was found between BCG Status and foreign bom patients (p-value <0.01) indicating a need for active screening of immigrants.
format	Thesis
qualification_name	Master of Philosophy (M.Phil.)
qualification_level	Master's degree
author	Azmi, Alia
author_facet	Azmi, Alia
author_sort	Azmi, Alia
title	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_short	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_full	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_fullStr	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_full_unstemmed	Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi
title_sort	prevalence of comorbidities & risk factors for multidrug resistance among tuberculosis patients in institute of respiratory medicine, kuala lumpur / alia azmi
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Architecture, Planning and Surveying
publishDate	2013
url	https://ir.uitm.edu.my/id/eprint/15474/1/TM_ALIA%20AZMI%20HS%2013_5.PDF
_version_	1783733405339353088

Prevalence of comorbidities & risk factors for Multidrug Resistance among Tuberculosis patients in Institute of Respiratory Medicine, Kuala Lumpur / Alia Azmi

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