Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim

There is a high prevalence of type 2 diabetes mellitus (T2DM) among obstructive sleep apnoea (OSA) patients; however the definite association between T2DM and other cardiovascular (CV) risk factors among OSA patients are not established. This study aims to determine the prevalence and associated ris...

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Main Author:	Ibrahim, Muhammad Amin
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Diabetes Mellitus
Online Access:	https://ir.uitm.edu.my/id/eprint/15964/1/TM_MUHAMMAD%20AMIN%20IBRAHIM%20MD%2015_5.pdf
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spelling	my-uitm-ir.159642022-03-10T02:18:36Z Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim 2015 Ibrahim, Muhammad Amin Diabetes Mellitus There is a high prevalence of type 2 diabetes mellitus (T2DM) among obstructive sleep apnoea (OSA) patients; however the definite association between T2DM and other cardiovascular (CV) risk factors among OSA patients are not established. This study aims to determine the prevalence and associated risk factors of T2DM among OSA patients. Methodology: A cross-sectional study from an OSA database in UiTM multidisciplinary sleep clinic between 1st January 2010 and 31st December 2014. Demographic and anthropometric indices, polysomnographic studies, cardiovascular risks-type2 diabetes mellitus, hypertension and dyslipidaemia, blood pressure readings and metabolic profiles (fasting plasma glucose, glycated haemoglobin, triglycerides and high-density-lipoprotein levels) were reviewed. Results: A total of 183 OSA patients were included in this study. The prevalence of T2DM is 49%, obesity is 91%, hypertension is 78% and dyslipidaemia is 67%. OSA patients with T2DM were associated with older age (54.5 vs. 47.2 years old, p 0.001), higher body mass index (38.2 vs. 35.8 kg/m , p 0.041) and higher systolic blood pressure (140 vs. 132 mmHg, p 0.01) in comparison to OSA patients without T2DM. In multivariate analysis, OSA patients with T2DM were associated with older age OR 1.04 (1.01- 1.07), higher BMI OR 1.005 (1.001-1.099), hypertension OR 4.2 (1.3-13.9) and dyslipidaemia OR 4.9 (2.1-11.4). Conclusion: The prevalence of T2DM among OSA patients was high and it was associated with older age, a higher body mass index, hypertension and dyslipidaemia. Therefore, screening for T2DM is recommended for all patients diagnosed with OSA 2015 Thesis https://ir.uitm.edu.my/id/eprint/15964/ https://ir.uitm.edu.my/id/eprint/15964/1/TM_MUHAMMAD%20AMIN%20IBRAHIM%20MD%2015_5.pdf text en public mphil masters Universiti Teknologi MARA Faculty of Medicine
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Diabetes Mellitus
spellingShingle	Diabetes Mellitus Ibrahim, Muhammad Amin Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim
description	There is a high prevalence of type 2 diabetes mellitus (T2DM) among obstructive sleep apnoea (OSA) patients; however the definite association between T2DM and other cardiovascular (CV) risk factors among OSA patients are not established. This study aims to determine the prevalence and associated risk factors of T2DM among OSA patients. Methodology: A cross-sectional study from an OSA database in UiTM multidisciplinary sleep clinic between 1st January 2010 and 31st December 2014. Demographic and anthropometric indices, polysomnographic studies, cardiovascular risks-type2 diabetes mellitus, hypertension and dyslipidaemia, blood pressure readings and metabolic profiles (fasting plasma glucose, glycated haemoglobin, triglycerides and high-density-lipoprotein levels) were reviewed. Results: A total of 183 OSA patients were included in this study. The prevalence of T2DM is 49%, obesity is 91%, hypertension is 78% and dyslipidaemia is 67%. OSA patients with T2DM were associated with older age (54.5 vs. 47.2 years old, p 0.001), higher body mass index (38.2 vs. 35.8 kg/m , p 0.041) and higher systolic blood pressure (140 vs. 132 mmHg, p 0.01) in comparison to OSA patients without T2DM. In multivariate analysis, OSA patients with T2DM were associated with older age OR 1.04 (1.01- 1.07), higher BMI OR 1.005 (1.001-1.099), hypertension OR 4.2 (1.3-13.9) and dyslipidaemia OR 4.9 (2.1-11.4). Conclusion: The prevalence of T2DM among OSA patients was high and it was associated with older age, a higher body mass index, hypertension and dyslipidaemia. Therefore, screening for T2DM is recommended for all patients diagnosed with OSA
format	Thesis
qualification_name	Master of Philosophy (M.Phil.)
qualification_level	Master's degree
author	Ibrahim, Muhammad Amin
author_facet	Ibrahim, Muhammad Amin
author_sort	Ibrahim, Muhammad Amin
title	Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim
title_short	Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim
title_full	Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim
title_fullStr	Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim
title_full_unstemmed	Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim
title_sort	prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / muhammad amin ibrahim
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Medicine
publishDate	2015
url	https://ir.uitm.edu.my/id/eprint/15964/1/TM_MUHAMMAD%20AMIN%20IBRAHIM%20MD%2015_5.pdf
_version_	1783733470162321408

Prevalence and associated risk factors of type 2 diabetes mellitus among obstructive sleep apnoea patients / Muhammad Amin Ibrahim

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