Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun

Acute coronary syndrome (ACS) patients often receive multiple medications during their hospitalization and this can lead to occurrence of drug-related problems (DRPs). They are normally presented together with other co-morbidities such as dyslipidemia, hypertension and diabetes that complicate more...

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Main Author:	Kimjun, Kuapih @ Florina
Format:	Thesis
Language:	English
Published:	2014
Subjects:	Drugs prescribing Drugs and their actions
Online Access:	https://ir.uitm.edu.my/id/eprint/21869/1/TM_KUAPIH%40FLORINA%20KIMJUN%20PH%20B%2014_5.pdf
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id	my-uitm-ir.21869
record_format	uketd_dc
spelling	my-uitm-ir.218692023-01-27T03:26:00Z Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun 2014 Kimjun, Kuapih @ Florina Drugs prescribing Drugs and their actions Acute coronary syndrome (ACS) patients often receive multiple medications during their hospitalization and this can lead to occurrence of drug-related problems (DRPs). They are normally presented together with other co-morbidities such as dyslipidemia, hypertension and diabetes that complicate more and have an influence on their drug choices during hospitalization. Therefore, this study is expected to give initial information on the type of DRPs and predictors of having DRPs during the episode of ACS patient hospitalization. Objective: To describe types and causes of DRPs in hospitalized acute coronary syndrome in Hospital Labuan. Factors associated with DRPs are determined and either DRPs have any impact on patient outcome in term of mortality. Method: A retrospective observational cohort study was conducted on 124 patients that were admitted to ward for diagnosis of either unstable angina, NSTEMI or STEMI. PCNE classification was used to categorize any drug related problems and its causes. Multiple logistic regressions analysis was performed to identify significant predictors of having DRPs from patient's characteristics. Results: An average of 1.38 ± 0.993 of DRPs per patient can be determined. About 78% of total subjects had at least one DRP. Highest number of DRPs were encountered under "treatment effectiveness" category (80.7%), followed by "adverse reactions" (12.3%) and "treatment costs" (7%). Length of hospital stay was the only significant predictor of having DRPs among the subjects (OR = 1.35; p = 0.045). No death was documented, thus DRPs impact on mortality cannot be identified. Conclusion: Small sample size and variability in the study design contribute to the inconsistency of the study findings from other DRPs studies carried out elsewhere. 2014 Thesis https://ir.uitm.edu.my/id/eprint/21869/ https://ir.uitm.edu.my/id/eprint/21869/1/TM_KUAPIH%40FLORINA%20KIMJUN%20PH%20B%2014_5.pdf text en public masters Universiti Teknologi MARA Faculty of Pharmacy
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Drugs prescribing Drugs and their actions
spellingShingle	Drugs prescribing Drugs and their actions Kimjun, Kuapih @ Florina Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun
description	Acute coronary syndrome (ACS) patients often receive multiple medications during their hospitalization and this can lead to occurrence of drug-related problems (DRPs). They are normally presented together with other co-morbidities such as dyslipidemia, hypertension and diabetes that complicate more and have an influence on their drug choices during hospitalization. Therefore, this study is expected to give initial information on the type of DRPs and predictors of having DRPs during the episode of ACS patient hospitalization. Objective: To describe types and causes of DRPs in hospitalized acute coronary syndrome in Hospital Labuan. Factors associated with DRPs are determined and either DRPs have any impact on patient outcome in term of mortality. Method: A retrospective observational cohort study was conducted on 124 patients that were admitted to ward for diagnosis of either unstable angina, NSTEMI or STEMI. PCNE classification was used to categorize any drug related problems and its causes. Multiple logistic regressions analysis was performed to identify significant predictors of having DRPs from patient's characteristics. Results: An average of 1.38 ± 0.993 of DRPs per patient can be determined. About 78% of total subjects had at least one DRP. Highest number of DRPs were encountered under "treatment effectiveness" category (80.7%), followed by "adverse reactions" (12.3%) and "treatment costs" (7%). Length of hospital stay was the only significant predictor of having DRPs among the subjects (OR = 1.35; p = 0.045). No death was documented, thus DRPs impact on mortality cannot be identified. Conclusion: Small sample size and variability in the study design contribute to the inconsistency of the study findings from other DRPs studies carried out elsewhere.
format	Thesis
qualification_level	Master's degree
author	Kimjun, Kuapih @ Florina
author_facet	Kimjun, Kuapih @ Florina
author_sort	Kimjun, Kuapih @ Florina
title	Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun
title_short	Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun
title_full	Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun
title_fullStr	Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun
title_full_unstemmed	Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun
title_sort	evaluation of drug related problems in hospitalized acute coronary syndrome patients / kuapih @ florina kimjun
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Pharmacy
publishDate	2014
url	https://ir.uitm.edu.my/id/eprint/21869/1/TM_KUAPIH%40FLORINA%20KIMJUN%20PH%20B%2014_5.pdf
_version_	1783733783019651072

Evaluation of drug related problems in hospitalized acute coronary syndrome patients / Kuapih @ Florina Kimjun

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