Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi

Artocarpus spp was identified to have numerous biological activity through an in vitro and in vivo pharmacological studies and these elucidated by the phenolic compounds such as flavonoids, stilbenoids, arylbenzofurons that present in different of plant parts. Mainly in the actual studies and review...

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Main Author:	Abdul Waled@Suhaimi, Abdul Muqit
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Antioxidants RS Pharmacy and materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/22288/1/TD_ABDUL%20MUQIT%20ABDUL%20WALED%20HS%20B%2015_5.pdf
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spelling	my-uitm-ir.222882018-12-26T06:28:08Z Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi 2015 Abdul Waled@Suhaimi, Abdul Muqit Antioxidants Antibiotic therapy. Antibiotics RS Pharmacy and materia medica Artocarpus spp was identified to have numerous biological activity through an in vitro and in vivo pharmacological studies and these elucidated by the phenolic compounds such as flavonoids, stilbenoids, arylbenzofurons that present in different of plant parts. Mainly in the actual studies and reviews on the antioxidant capability of natural product focus more on the characteristics of the measurement procedure for instance free radical generating system, redox process and hydrophilic solubility. Nevertheless, the vital steps such as preparation of sample or the procedure for extraction of antioxidants compound were not concentrated critically. Thus far, less attention in systematic analysis of the effects of different drying methods on the total flavonoid content and antioxidant activity of Artocarpus heterophyllus Lam (jackfruit) leaf extract. This study is aim to determine the effects of different drying methods on the phenolic and flavonoid content and the antioxidant capacity of Artocarpus heterophyllus Lam (jackfruit) leaf aqueous and ethanolic extract. Jackfruit leaves were subjected to three different drying methods such as, sun drying, oven drying and air drying. The weight loss of the oven-dried, sun-dried and airdried samples will be recorded at time intervals and the drying experiments will be conducted in triplicate. Drying process were be stop when no significant changes in three consecutive weight. 10% aqueous and 70% ethanol extraction was chosen in these experiments to obtain a crude extract of freeze dry powder and dark-green viscous mass crude extract from rotary evaporation. Analysis of total phenolic and flavonoid contents as well as its antioxidant capacity and ferric reducing power of jackfruit leaf extract were then determined. The total phenolic content (TPC) of ethanolic and aqueous extracts was significantly different as affected by different drying treatments, with air dried and oven dried produce slightly decrease in TPC and antioxidant activity as demonstrated by the reduction in both free radical scavenging activity of DPPH and lowering the FRAP values. Oven dried extract causing the highest decrease in TPC and antioxidant activity. However, sun dried jackfruit leaves extracts possessed a high TPC and antioxidant activity compared to the air and oven drying hence suggesting that sun dried methods is the most preferable method for processing Artocarpus heterophyllus Lam (jackfruit) leaves in order to preserve the antioxidant properties, phenolic content as well as total flavonoids content. 2015 Thesis https://ir.uitm.edu.my/id/eprint/22288/ https://ir.uitm.edu.my/id/eprint/22288/1/TD_ABDUL%20MUQIT%20ABDUL%20WALED%20HS%20B%2015_5.pdf text en public degree Universiti Teknologi MARA, Selangor, Puncak Alam Campus Faculty of Health Science
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Antioxidants Antioxidants RS Pharmacy and materia medica
spellingShingle	Antioxidants Antioxidants RS Pharmacy and materia medica Abdul Waled@Suhaimi, Abdul Muqit Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi
description	Artocarpus spp was identified to have numerous biological activity through an in vitro and in vivo pharmacological studies and these elucidated by the phenolic compounds such as flavonoids, stilbenoids, arylbenzofurons that present in different of plant parts. Mainly in the actual studies and reviews on the antioxidant capability of natural product focus more on the characteristics of the measurement procedure for instance free radical generating system, redox process and hydrophilic solubility. Nevertheless, the vital steps such as preparation of sample or the procedure for extraction of antioxidants compound were not concentrated critically. Thus far, less attention in systematic analysis of the effects of different drying methods on the total flavonoid content and antioxidant activity of Artocarpus heterophyllus Lam (jackfruit) leaf extract. This study is aim to determine the effects of different drying methods on the phenolic and flavonoid content and the antioxidant capacity of Artocarpus heterophyllus Lam (jackfruit) leaf aqueous and ethanolic extract. Jackfruit leaves were subjected to three different drying methods such as, sun drying, oven drying and air drying. The weight loss of the oven-dried, sun-dried and airdried samples will be recorded at time intervals and the drying experiments will be conducted in triplicate. Drying process were be stop when no significant changes in three consecutive weight. 10% aqueous and 70% ethanol extraction was chosen in these experiments to obtain a crude extract of freeze dry powder and dark-green viscous mass crude extract from rotary evaporation. Analysis of total phenolic and flavonoid contents as well as its antioxidant capacity and ferric reducing power of jackfruit leaf extract were then determined. The total phenolic content (TPC) of ethanolic and aqueous extracts was significantly different as affected by different drying treatments, with air dried and oven dried produce slightly decrease in TPC and antioxidant activity as demonstrated by the reduction in both free radical scavenging activity of DPPH and lowering the FRAP values. Oven dried extract causing the highest decrease in TPC and antioxidant activity. However, sun dried jackfruit leaves extracts possessed a high TPC and antioxidant activity compared to the air and oven drying hence suggesting that sun dried methods is the most preferable method for processing Artocarpus heterophyllus Lam (jackfruit) leaves in order to preserve the antioxidant properties, phenolic content as well as total flavonoids content.
format	Thesis
qualification_level	Bachelor degree
author	Abdul Waled@Suhaimi, Abdul Muqit
author_facet	Abdul Waled@Suhaimi, Abdul Muqit
author_sort	Abdul Waled@Suhaimi, Abdul Muqit
title	Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi
title_short	Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi
title_full	Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi
title_fullStr	Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi
title_full_unstemmed	Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi
title_sort	effect of different drying method on antioxidant capacity and total flavonoid contents of artocarpus heterophyllus lam. (jackfruit) leaf extract / abdul muqit abdul waled@suhaimi
granting_institution	Universiti Teknologi MARA, Selangor, Puncak Alam Campus
granting_department	Faculty of Health Science
publishDate	2015
url	https://ir.uitm.edu.my/id/eprint/22288/1/TD_ABDUL%20MUQIT%20ABDUL%20WALED%20HS%20B%2015_5.pdf
_version_	1783733803925110784

Effect of different drying method on antioxidant capacity and total flavonoid contents of Artocarpus Heterophyllus Lam. (Jackfruit) leaf extract / Abdul Muqit Abdul Waled@Suhaimi

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