Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan

Centella asiatica is a small, herbaceous, and creeping plant that ubiquitously growth in moist area around South East Asia that known to possess the neuroprotective agent that help in learning and memory enhancement. The present study aims to demonstrate the effect of different type of Centella asa...

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Main Author:	Hassan, Ahmad Fakhriy
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/22289/1/TD_AHMAD%20FAKHRIY%20HASSAN%20HS%20B%2015_5.pdf
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id	my-uitm-ir.22289
record_format	uketd_dc
spelling	my-uitm-ir.222892021-07-27T04:37:14Z Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan 2015 Hassan, Ahmad Fakhriy Materia medica Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Centella asiatica is a small, herbaceous, and creeping plant that ubiquitously growth in moist area around South East Asia that known to possess the neuroprotective agent that help in learning and memory enhancement. The present study aims to demonstrate the effect of different type of Centella asaitica (big and small type) fresh extarct on learning and memory enhancement by using histological finding. Both type of Centella asiatica fresh extract were given orally 6, 12 and 24 mg/kg for 6 weeks. After the treatment, the rats were sacrificed, their brain were removed and the brain hippocampus impregnated with cresyl violet staining. The brain sectioning were observed for thickness of dentate gyrus and neuronal cell death by using light microscope. The result obtained showed that both type of Centella asiatica showed increased in thickness of dentate gyrus as compared to control group. For neuronal cell death, both type of Centella asiatica showed reduced in number of cell death at hippocampus region. In conclusion, this study indicate that both type of Centella asiatica fresh extract possessed neuroprotective agent that help in learning and memory enhancement. 2015 Thesis https://ir.uitm.edu.my/id/eprint/22289/ https://ir.uitm.edu.my/id/eprint/22289/1/TD_AHMAD%20FAKHRIY%20HASSAN%20HS%20B%2015_5.pdf text en public degree Universiti Teknologi MARA, Selangor, Puncak Alam Campus Faculty of Health Science Zakaria, Fatin Nadzirah
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Zakaria, Fatin Nadzirah
topic	Materia medica Materia medica
spellingShingle	Materia medica Materia medica Hassan, Ahmad Fakhriy Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan
description	Centella asiatica is a small, herbaceous, and creeping plant that ubiquitously growth in moist area around South East Asia that known to possess the neuroprotective agent that help in learning and memory enhancement. The present study aims to demonstrate the effect of different type of Centella asaitica (big and small type) fresh extarct on learning and memory enhancement by using histological finding. Both type of Centella asiatica fresh extract were given orally 6, 12 and 24 mg/kg for 6 weeks. After the treatment, the rats were sacrificed, their brain were removed and the brain hippocampus impregnated with cresyl violet staining. The brain sectioning were observed for thickness of dentate gyrus and neuronal cell death by using light microscope. The result obtained showed that both type of Centella asiatica showed increased in thickness of dentate gyrus as compared to control group. For neuronal cell death, both type of Centella asiatica showed reduced in number of cell death at hippocampus region. In conclusion, this study indicate that both type of Centella asiatica fresh extract possessed neuroprotective agent that help in learning and memory enhancement.
format	Thesis
qualification_level	Bachelor degree
author	Hassan, Ahmad Fakhriy
author_facet	Hassan, Ahmad Fakhriy
author_sort	Hassan, Ahmad Fakhriy
title	Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan
title_short	Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan
title_full	Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan
title_fullStr	Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan
title_full_unstemmed	Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan
title_sort	effect of fresh extract of centella asiatica (big type) and centella asiatica (small type) in learning and memory enhancement / ahmad fakhriy hassan
granting_institution	Universiti Teknologi MARA, Selangor, Puncak Alam Campus
granting_department	Faculty of Health Science
publishDate	2015
url	https://ir.uitm.edu.my/id/eprint/22289/1/TD_AHMAD%20FAKHRIY%20HASSAN%20HS%20B%2015_5.pdf
_version_	1783733804169428992

Effect of fresh extract of Centella Asiatica (Big type) and Centella Asiatica (Small type) in learning and memory enhancement / Ahmad Fakhriy Hassan

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