Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin

Cardiovascular diseases (CVDs) are leading health problems caused by several risk factors, which include obesity. Obesity is defined as abnormal or excessive fat accumulation that may impair health and is the fifth leading risk for global deaths. Wet cupping therapy (WCT) is a recognized Malay tradi...

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Main Author:	Md Yassin, Mohd Anwar
Format:	Thesis
Language:	English
Published:	2019
Subjects:	Examination of the blood
Online Access:	https://ir.uitm.edu.my/id/eprint/27734/1/TM_MOHD%20ANWAR%20MD%20YASSIN%20PH%2019_5.pdf
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id	my-uitm-ir.27734
record_format	uketd_dc
spelling	my-uitm-ir.277342020-01-24T08:32:57Z Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin 2019 Md Yassin, Mohd Anwar Examination of the blood Cardiovascular diseases (CVDs) are leading health problems caused by several risk factors, which include obesity. Obesity is defined as abnormal or excessive fat accumulation that may impair health and is the fifth leading risk for global deaths. Wet cupping therapy (WCT) is a recognized Malay traditional medicine that was shown pre-clinically to be effective against CVD parameters. This study was conducted to determine effects ofWCT on blood parameters and quality of life (QoL) of obese male individuals at baseline, pre- and post-WCT sessions and to look for differences between venous and cupping bloods samples. Obese male participants aged 22 until 39 years old were recruited with informed consent to receive two WCT sessions. Blood was collected via venipuncture from all participants at baseline, pre-and post-WCT sessions. Wet cupping sessions were conducted on days 28th and 35th. Venous and cupping blood samples were collected and analyzed. Study participants answer questionnaires related to quality of life. There were significant increase in aspartate transaminase (p < 0.05) and significant decrease in total protein (p < 0.001) between baseline, pre- and post-WCT sessions. Hematological parameters remained unchanged after WCT. Metabolite pathways via log fold change analysis uncovered insignificant regulation between baseline - pre-cupping venous bloods (p > 0.05), significant down regulation between pre-cupping - post-cupping (p < 0.001), and significant metabolites up regulation in cupping as compared to venous blood ( p ~ 0.001), including linoleic acid (LA), sphingosine I-phosphate (SIP) and glycochenodeoxycholate (GCDC). Three cupping points of WCT were found to affect several blood parameters and metabolic pathways associated with CVD. This findings provide evidence that WCT may be utilized as adjuvant treatment management against CVDs and obesity. 2019 Thesis https://ir.uitm.edu.my/id/eprint/27734/ https://ir.uitm.edu.my/id/eprint/27734/1/TM_MOHD%20ANWAR%20MD%20YASSIN%20PH%2019_5.pdf text en public masters Universiti Teknologi MARA Faculty of Pharmacy
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Examination of the blood
spellingShingle	Examination of the blood Md Yassin, Mohd Anwar Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin
description	Cardiovascular diseases (CVDs) are leading health problems caused by several risk factors, which include obesity. Obesity is defined as abnormal or excessive fat accumulation that may impair health and is the fifth leading risk for global deaths. Wet cupping therapy (WCT) is a recognized Malay traditional medicine that was shown pre-clinically to be effective against CVD parameters. This study was conducted to determine effects ofWCT on blood parameters and quality of life (QoL) of obese male individuals at baseline, pre- and post-WCT sessions and to look for differences between venous and cupping bloods samples. Obese male participants aged 22 until 39 years old were recruited with informed consent to receive two WCT sessions. Blood was collected via venipuncture from all participants at baseline, pre-and post-WCT sessions. Wet cupping sessions were conducted on days 28th and 35th. Venous and cupping blood samples were collected and analyzed. Study participants answer questionnaires related to quality of life. There were significant increase in aspartate transaminase (p < 0.05) and significant decrease in total protein (p < 0.001) between baseline, pre- and post-WCT sessions. Hematological parameters remained unchanged after WCT. Metabolite pathways via log fold change analysis uncovered insignificant regulation between baseline - pre-cupping venous bloods (p > 0.05), significant down regulation between pre-cupping - post-cupping (p < 0.001), and significant metabolites up regulation in cupping as compared to venous blood ( p ~ 0.001), including linoleic acid (LA), sphingosine I-phosphate (SIP) and glycochenodeoxycholate (GCDC). Three cupping points of WCT were found to affect several blood parameters and metabolic pathways associated with CVD. This findings provide evidence that WCT may be utilized as adjuvant treatment management against CVDs and obesity.
format	Thesis
qualification_level	Master's degree
author	Md Yassin, Mohd Anwar
author_facet	Md Yassin, Mohd Anwar
author_sort	Md Yassin, Mohd Anwar
title	Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin
title_short	Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin
title_full	Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin
title_fullStr	Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin
title_full_unstemmed	Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin
title_sort	effects of wet cupping therapy on blood parameters and quality of life of obese individuals / mohd anwar md yassin
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Pharmacy
publishDate	2019
url	https://ir.uitm.edu.my/id/eprint/27734/1/TM_MOHD%20ANWAR%20MD%20YASSIN%20PH%2019_5.pdf
_version_	1783734004530282496

Effects of wet cupping therapy on blood parameters and quality of life of obese individuals / Mohd Anwar Md Yassin

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