Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf

Spreading of Candidiasis cause by Candida albicans required more effective treatment that is not harmful to the patient. The presence of antioxidant properties could be a treatment for debilitating disease from free radical that contains with high reactive compound, which contributes to damage many...

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Main Author:	Mohammad Yusuf, Shafinaz
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Antibiotic therapy Antibiotics
Online Access:	https://ir.uitm.edu.my/id/eprint/27852/1/TD_SHAFINAZ%20MOHAMMAD%20YUSUF%20HS%2015_5.pdf
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id	my-uitm-ir.27852
record_format	uketd_dc
spelling	my-uitm-ir.278522020-01-29T04:47:49Z Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf 2015 Mohammad Yusuf, Shafinaz Antibiotic therapy. Antibiotics Spreading of Candidiasis cause by Candida albicans required more effective treatment that is not harmful to the patient. The presence of antioxidant properties could be a treatment for debilitating disease from free radical that contains with high reactive compound, which contributes to damage many structures of cell in human body. Morus nigra L (black mulberry) native from China is popular as the traditional herb due to the medicinal properties and phytochemical composition. The present study was designed to observe the antimycotic properties against Candida albicans (ATCC 60193) and antioxidant activity of Morus nigra L leaves extract grown in Malaysia. Antimycotic effect of Morus nigra L leaves extract was evaluated by Minimimum Inhibitory Concentration (MIC), Minimum Fungicidal Concentration (MFC) and Antimycotic Sensitivity Testing (AST). For antioxidant activities evaluation, the DPPH radical scavenging assay was carried out. The methanol extract of Morus nigra L leaves extract was found to be active against Candida albicans and it was determined to have antioxidant activities. The Minimum Inhibitory Concentration (MIC) determined to be 37.5mg/ml and Minimum Fungicidal Concentration (MFC) for methanol extract of Morus nigra L leaves were determined to be 75.5mg/ml while the Antimycotic Sensitivity Testing showed effects of the inhibition zone on PDA media for concentration 1000mg/ml, 500mg/ml, 250mg/ml and 75.5mg/m. Besides, the results of comparison between Morus nigra L and L-ascorbic acid in antioxidant activity proved that there are significantly (p<0.05). It revealed that methanolic extract of the Morus nigra L leaves contain potential antioxidant activity. 2015 Thesis https://ir.uitm.edu.my/id/eprint/27852/ https://ir.uitm.edu.my/id/eprint/27852/1/TD_SHAFINAZ%20MOHAMMAD%20YUSUF%20HS%2015_5.pdf text en public degree Universiti Teknologi MARA Faculty of Health Sciences
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Antibiotic therapy Antibiotics
spellingShingle	Antibiotic therapy Antibiotics Mohammad Yusuf, Shafinaz Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf
description	Spreading of Candidiasis cause by Candida albicans required more effective treatment that is not harmful to the patient. The presence of antioxidant properties could be a treatment for debilitating disease from free radical that contains with high reactive compound, which contributes to damage many structures of cell in human body. Morus nigra L (black mulberry) native from China is popular as the traditional herb due to the medicinal properties and phytochemical composition. The present study was designed to observe the antimycotic properties against Candida albicans (ATCC 60193) and antioxidant activity of Morus nigra L leaves extract grown in Malaysia. Antimycotic effect of Morus nigra L leaves extract was evaluated by Minimimum Inhibitory Concentration (MIC), Minimum Fungicidal Concentration (MFC) and Antimycotic Sensitivity Testing (AST). For antioxidant activities evaluation, the DPPH radical scavenging assay was carried out. The methanol extract of Morus nigra L leaves extract was found to be active against Candida albicans and it was determined to have antioxidant activities. The Minimum Inhibitory Concentration (MIC) determined to be 37.5mg/ml and Minimum Fungicidal Concentration (MFC) for methanol extract of Morus nigra L leaves were determined to be 75.5mg/ml while the Antimycotic Sensitivity Testing showed effects of the inhibition zone on PDA media for concentration 1000mg/ml, 500mg/ml, 250mg/ml and 75.5mg/m. Besides, the results of comparison between Morus nigra L and L-ascorbic acid in antioxidant activity proved that there are significantly (p<0.05). It revealed that methanolic extract of the Morus nigra L leaves contain potential antioxidant activity.
format	Thesis
qualification_level	Bachelor degree
author	Mohammad Yusuf, Shafinaz
author_facet	Mohammad Yusuf, Shafinaz
author_sort	Mohammad Yusuf, Shafinaz
title	Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf
title_short	Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf
title_full	Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf
title_fullStr	Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf
title_full_unstemmed	Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf
title_sort	determination of antimycotic and antioxidant activities in morus nigra l (black mulberry) leaves extract grown in malaysia / shafinaz mohammad yusuf
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Health Sciences
publishDate	2015
url	https://ir.uitm.edu.my/id/eprint/27852/1/TD_SHAFINAZ%20MOHAMMAD%20YUSUF%20HS%2015_5.pdf
_version_	1783734019673817088

Determination of antimycotic and antioxidant activities in Morus nigra L (black mulberry) leaves extract grown in Malaysia / Shafinaz Mohammad Yusuf

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