Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa

Melastoma malabathricum and Chromoalaena odorata are traditional remedies used by Asian, generally to heal the wound. To date, no data on comparison of percentage wound healing between Melastoma malabathricum leaves extract and Chromolaena odorata leaves extract been studied. Current study was desig...

Full description

Saved in:

Bibliographic Details
Main Author:	Mustapa, Siti Muzaifah
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Antioxidants
Online Access:	https://ir.uitm.edu.my/id/eprint/27892/1/TD_SITI%20MUZAIFAH%20MUSTAPA%20HS%2015_5.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-uitm-ir.27892
record_format	uketd_dc
spelling	my-uitm-ir.278922020-01-30T03:47:34Z Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa 2015 Mustapa, Siti Muzaifah Antioxidants Clinical pathology. Laboratory technique Melastoma malabathricum and Chromoalaena odorata are traditional remedies used by Asian, generally to heal the wound. To date, no data on comparison of percentage wound healing between Melastoma malabathricum leaves extract and Chromolaena odorata leaves extract been studied. Current study was designed to compare wound healing activities between M.malabathricum leaves extract and C.odorata leaves extract in vivo. Phytochemical analysis for both herbal plants also had been done by using methanol solvent to determine concentration of flavonoid and tannin. Sixteen male Sprague dawley rats used as excisional wound model and wound was created with area 4cm2 on their dorsal by using scalpel after acclimatized for two weeks. They were divided to four groups whereby each group was gave different treatment that were group I: gentamicin cream, group II: 10% Melastoma malabathricum ointment, group III: 10% Chromolaena odorata ointment and group IV: Vaseline and in three days interval until fifteenth day percentage of wound area was measured and calculated. M. malabathricum leaves extract consist higher concentration of flavonoids and tannins compare to the C. odorata leaves extract and visually, M. malabathricum leaves extract accelerate wound healing faster than C. ododrata leaves extract, as the concentration of flavonoids and tannins were high. Statistically the result was not significant. In conclusion, M. malabathricum leaves extract and C. odorata leaves extract do show potential asset that can be used for development of alternative remedy. 2015 Thesis https://ir.uitm.edu.my/id/eprint/27892/ https://ir.uitm.edu.my/id/eprint/27892/1/TD_SITI%20MUZAIFAH%20MUSTAPA%20HS%2015_5.pdf text en public degree Universiti Teknologi MARA Faculty of Health Sciences
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Antioxidants Antioxidants
spellingShingle	Antioxidants Antioxidants Mustapa, Siti Muzaifah Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
description	Melastoma malabathricum and Chromoalaena odorata are traditional remedies used by Asian, generally to heal the wound. To date, no data on comparison of percentage wound healing between Melastoma malabathricum leaves extract and Chromolaena odorata leaves extract been studied. Current study was designed to compare wound healing activities between M.malabathricum leaves extract and C.odorata leaves extract in vivo. Phytochemical analysis for both herbal plants also had been done by using methanol solvent to determine concentration of flavonoid and tannin. Sixteen male Sprague dawley rats used as excisional wound model and wound was created with area 4cm2 on their dorsal by using scalpel after acclimatized for two weeks. They were divided to four groups whereby each group was gave different treatment that were group I: gentamicin cream, group II: 10% Melastoma malabathricum ointment, group III: 10% Chromolaena odorata ointment and group IV: Vaseline and in three days interval until fifteenth day percentage of wound area was measured and calculated. M. malabathricum leaves extract consist higher concentration of flavonoids and tannins compare to the C. odorata leaves extract and visually, M. malabathricum leaves extract accelerate wound healing faster than C. ododrata leaves extract, as the concentration of flavonoids and tannins were high. Statistically the result was not significant. In conclusion, M. malabathricum leaves extract and C. odorata leaves extract do show potential asset that can be used for development of alternative remedy.
format	Thesis
qualification_level	Bachelor degree
author	Mustapa, Siti Muzaifah
author_facet	Mustapa, Siti Muzaifah
author_sort	Mustapa, Siti Muzaifah
title	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_short	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_full	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_fullStr	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_full_unstemmed	Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa
title_sort	evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / siti muzaifah mustapa
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Health Sciences
publishDate	2015
url	https://ir.uitm.edu.my/id/eprint/27892/1/TD_SITI%20MUZAIFAH%20MUSTAPA%20HS%2015_5.pdf
_version_	1783734023984513024

Evaluation of wound healing activities between melastoma malabathricum leaves extract and chromolaena odorata leaves extract in male sprague dawley rats / Siti Muzaifah Mustapa

Similar Items