Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias

Free radicals is the unstable molecules that can damage the cells. Free radical occurs from the digestion of food or breathing in polluted air. In order to protect cells in body from free radical, antioxidant is the nutrient that help to prevent from damaging of the cells. Antioxidant can be founded...

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Main Author:	Alias, Muhammad Saddam Hussein
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Antioxidants
Online Access:	https://ir.uitm.edu.my/id/eprint/27988/1/TD_MUHAMMAD%20SADDAM%20HUSSEIN%20ALIAS%20HS%2015_5.pdf
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id	my-uitm-ir.27988
record_format	uketd_dc
spelling	my-uitm-ir.279882020-01-31T01:53:21Z Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias 2015 Alias, Muhammad Saddam Hussein Antioxidants Clinical pathology. Laboratory technique Free radicals is the unstable molecules that can damage the cells. Free radical occurs from the digestion of food or breathing in polluted air. In order to protect cells in body from free radical, antioxidant is the nutrient that help to prevent from damaging of the cells. Antioxidant can be founded in food or supplementation. The damaging of cells may increase the risk of getting cancer, heart disease, diabetes, or infections. Therefore, the need for antioxidants becomes even more critical with increased exposure to free radicals. In industries, the synthetic antioxidant is widely used such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) even thought it could lead to negative health effect. In recent years, a lot of herbal medicine is used as the alternative therapy. Centella asiatica has been claimed that have many physiological effect and its traditionally used. However, there was lack of data reported on antioxidant activity using Centella asiatica fresh extraction. Thus, in this study is focusing on antioxidant activities of 1, I-diphenyl2- picrylhydrazyl (DPPH), Ferric Reducing Antioxidant Potential (FRAP), total phenolic contain (TPC) and total flavonoid content (TFC) in small size cultivar and large size cultivar of Centella asiatica. At the end ofthe experiment, the TFC has shown increase in antioxidant activity of small cultivar and large cultivar with value 489.84 quercetin equivalent Ig extract and 350 quercetin equivalent Ig extract, compare to the control (p<0.05). On the other hand, the correlation study show the DPPH and FRAP is highly correlated with TPC and TFC. In conclusion, this finding suggested that Centella asiatica possesses antioxidant activity. 2015 Thesis https://ir.uitm.edu.my/id/eprint/27988/ https://ir.uitm.edu.my/id/eprint/27988/1/TD_MUHAMMAD%20SADDAM%20HUSSEIN%20ALIAS%20HS%2015_5.pdf text en public degree Universiti Teknologi MARA Faculty of Health Sciences
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Antioxidants Antioxidants
spellingShingle	Antioxidants Antioxidants Alias, Muhammad Saddam Hussein Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias
description	Free radicals is the unstable molecules that can damage the cells. Free radical occurs from the digestion of food or breathing in polluted air. In order to protect cells in body from free radical, antioxidant is the nutrient that help to prevent from damaging of the cells. Antioxidant can be founded in food or supplementation. The damaging of cells may increase the risk of getting cancer, heart disease, diabetes, or infections. Therefore, the need for antioxidants becomes even more critical with increased exposure to free radicals. In industries, the synthetic antioxidant is widely used such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) even thought it could lead to negative health effect. In recent years, a lot of herbal medicine is used as the alternative therapy. Centella asiatica has been claimed that have many physiological effect and its traditionally used. However, there was lack of data reported on antioxidant activity using Centella asiatica fresh extraction. Thus, in this study is focusing on antioxidant activities of 1, I-diphenyl2- picrylhydrazyl (DPPH), Ferric Reducing Antioxidant Potential (FRAP), total phenolic contain (TPC) and total flavonoid content (TFC) in small size cultivar and large size cultivar of Centella asiatica. At the end ofthe experiment, the TFC has shown increase in antioxidant activity of small cultivar and large cultivar with value 489.84 quercetin equivalent Ig extract and 350 quercetin equivalent Ig extract, compare to the control (p<0.05). On the other hand, the correlation study show the DPPH and FRAP is highly correlated with TPC and TFC. In conclusion, this finding suggested that Centella asiatica possesses antioxidant activity.
format	Thesis
qualification_level	Bachelor degree
author	Alias, Muhammad Saddam Hussein
author_facet	Alias, Muhammad Saddam Hussein
author_sort	Alias, Muhammad Saddam Hussein
title	Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias
title_short	Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias
title_full	Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias
title_fullStr	Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias
title_full_unstemmed	Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias
title_sort	antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of centella asiatica / muhammad saddam hussein alias
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Health Sciences
publishDate	2015
url	https://ir.uitm.edu.my/id/eprint/27988/1/TD_MUHAMMAD%20SADDAM%20HUSSEIN%20ALIAS%20HS%2015_5.pdf
_version_	1783734033260216320

Antioxidant activities, total phenolic and flavonoid content in small size cultivar and large size cultivar of Centella asiatica / Muhammad Saddam Hussein Alias

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