Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri

Biosynthesis of silver nanoparticles using plant extracts are currently being explored as an alternative approach in pharmaceutical and medical field. The aims of this study was synthesized and characterized silver nanoparticles (AgNPs) by using UV-Vis spectrophotometer, identified their antibacteri...

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Main Author:	Satteri, Nur Syazana
Format:	Thesis
Language:	English
Published:	2020
Subjects:	Extraction (Chemistry) Toxicity testing Bacteria
Online Access:	https://ir.uitm.edu.my/id/eprint/36474/1/36474.pdf
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id	my-uitm-ir.36474
record_format	uketd_dc
spelling	my-uitm-ir.364742020-11-12T02:53:19Z Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri 2020-11-09 Satteri, Nur Syazana Extraction (Chemistry) Toxicity testing Bacteria Biosynthesis of silver nanoparticles using plant extracts are currently being explored as an alternative approach in pharmaceutical and medical field. The aims of this study was synthesized and characterized silver nanoparticles (AgNPs) by using UV-Vis spectrophotometer, identified their antibacterial and toxicity activity. The biosynthesized of AgNPs were varies in the reaction time (1, 2, 3, 6 and 7) days, was characterized by UV-Vis spectrophotometer (200-600 nm). The determination of antibacterial and toxicity assays of Lawsonia inermis was done by Kirby–Bauer disc diffusion method (Gram-positive and Gram-negative bacterial strains) and Brine Shrimp Lethality Assay respectively. From the result, L. inermis leaf extract was reduced the silver ions and indicates the formation of silver nanoparticles by changing colour from dark brown to colloidal grey. The highest peak of biosynthesized silver nanoparticles from L. inermis extract in range from 420 nm to 471 nm. Zone inhibition for Gram-positive and Gram-negative bacterial strains at 1000 μg/ml was 12.00 mm and 12.33 mm respectively. The LC50 of biosynthesized AgNPs at 1000 μg/ml was observed 7367.233 which indicate non-toxic towards the brine shrimp. To conclude, AgNPs synthesized from L. inermis leaves extract would be very efficient to be an alternative for antibacterial. 2020-11 Thesis https://ir.uitm.edu.my/id/eprint/36474/ https://ir.uitm.edu.my/id/eprint/36474/1/36474.pdf text en public degree Universiti Teknologi Mara Perlis Faculty of Applied Sciences
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Extraction (Chemistry) Toxicity testing Bacteria
spellingShingle	Extraction (Chemistry) Toxicity testing Bacteria Satteri, Nur Syazana Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri
description	Biosynthesis of silver nanoparticles using plant extracts are currently being explored as an alternative approach in pharmaceutical and medical field. The aims of this study was synthesized and characterized silver nanoparticles (AgNPs) by using UV-Vis spectrophotometer, identified their antibacterial and toxicity activity. The biosynthesized of AgNPs were varies in the reaction time (1, 2, 3, 6 and 7) days, was characterized by UV-Vis spectrophotometer (200-600 nm). The determination of antibacterial and toxicity assays of Lawsonia inermis was done by Kirby–Bauer disc diffusion method (Gram-positive and Gram-negative bacterial strains) and Brine Shrimp Lethality Assay respectively. From the result, L. inermis leaf extract was reduced the silver ions and indicates the formation of silver nanoparticles by changing colour from dark brown to colloidal grey. The highest peak of biosynthesized silver nanoparticles from L. inermis extract in range from 420 nm to 471 nm. Zone inhibition for Gram-positive and Gram-negative bacterial strains at 1000 μg/ml was 12.00 mm and 12.33 mm respectively. The LC50 of biosynthesized AgNPs at 1000 μg/ml was observed 7367.233 which indicate non-toxic towards the brine shrimp. To conclude, AgNPs synthesized from L. inermis leaves extract would be very efficient to be an alternative for antibacterial.
format	Thesis
qualification_level	Bachelor degree
author	Satteri, Nur Syazana
author_facet	Satteri, Nur Syazana
author_sort	Satteri, Nur Syazana
title	Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri
title_short	Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri
title_full	Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri
title_fullStr	Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri
title_full_unstemmed	Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri
title_sort	antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / nur syazana satteri
granting_institution	Universiti Teknologi Mara Perlis
granting_department	Faculty of Applied Sciences
publishDate	2020
url	https://ir.uitm.edu.my/id/eprint/36474/1/36474.pdf
_version_	1783734338805825536

Antibacterial and toxicity properties of biosynthesized silver nanoparticles by lawsonia inermis extract / Nur Syazana Satteri

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