The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila

The multiple drug resistance (MDR) become the biggest concern to the experts in microbiology area as this problem might contribute to failure in the prevalence of bacterial infections. Alternatives were found basically through natural product among the researchers, in order to combat the prevalence...

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Main Author:	Normila, Intan Alyani
Format:	Thesis
Language:	English
Published:	2017
Subjects:	QR Microbiology Drugs and their actions Materia medica
Online Access:	https://ir.uitm.edu.my/id/eprint/50140/1/50140.pdf
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id	my-uitm-ir.50140
record_format	uketd_dc
spelling	my-uitm-ir.501402021-09-07T01:32:22Z The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila 2017 Normila, Intan Alyani QR Microbiology Antibiotic therapy. Antibiotics Drugs and their actions Materia medica The multiple drug resistance (MDR) become the biggest concern to the experts in microbiology area as this problem might contribute to failure in the prevalence of bacterial infections. Alternatives were found basically through natural product among the researchers, in order to combat the prevalence of global antimicrobial resistance problem. Parkia speciosa has been reported in the previous study, to have antimicrobial agent properties in the seeds and pods. However, besides seeds, there are more compartments on the plant that been neglected which suggested to contain the same therapeutic properties. Therefore, this study was conducted to assess the antimicrobial activity of Parkia Speciosa leaves extract against Staphylococcus aureus and Escherichia coli. An experimental research design was carried out which involved Antibiotic Susceptibility Test (AST), Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC). The data were analyzed using ANOVA. Methanolic extract of Parkia speciose leaves gives best significant antimicrobial activity against Staphylococcus aureus. While no antimicrobial activity can be observed on Escherichia coli. The MIC and MBC of Staphylococcus aureus were performed in triplicate and showed the significant result (p<0.05). As for MIC, the result showed minimal concentration that can inhibit the bacteria is 31.25 mg/ml. However, the MBC value against Staphylococcus aureus was detected at 500 mg/ml. Based on that, this study revealed that methanolic extract of Parkia speciosa leaves has potential to be used as an antimicrobial agent against gram-positive bacteria Staphylococcus aureus more effectively than gram negative bacteria, Escherichia coli. 2017 Thesis https://ir.uitm.edu.my/id/eprint/50140/ https://ir.uitm.edu.my/id/eprint/50140/1/50140.pdf text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Health Sciences Abdul Hamid, Zed Zakari
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Abdul Hamid, Zed Zakari
topic	QR Microbiology QR Microbiology Drugs and their actions Materia medica
spellingShingle	QR Microbiology QR Microbiology Drugs and their actions Materia medica Normila, Intan Alyani The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila
description	The multiple drug resistance (MDR) become the biggest concern to the experts in microbiology area as this problem might contribute to failure in the prevalence of bacterial infections. Alternatives were found basically through natural product among the researchers, in order to combat the prevalence of global antimicrobial resistance problem. Parkia speciosa has been reported in the previous study, to have antimicrobial agent properties in the seeds and pods. However, besides seeds, there are more compartments on the plant that been neglected which suggested to contain the same therapeutic properties. Therefore, this study was conducted to assess the antimicrobial activity of Parkia Speciosa leaves extract against Staphylococcus aureus and Escherichia coli. An experimental research design was carried out which involved Antibiotic Susceptibility Test (AST), Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC). The data were analyzed using ANOVA. Methanolic extract of Parkia speciose leaves gives best significant antimicrobial activity against Staphylococcus aureus. While no antimicrobial activity can be observed on Escherichia coli. The MIC and MBC of Staphylococcus aureus were performed in triplicate and showed the significant result (p<0.05). As for MIC, the result showed minimal concentration that can inhibit the bacteria is 31.25 mg/ml. However, the MBC value against Staphylococcus aureus was detected at 500 mg/ml. Based on that, this study revealed that methanolic extract of Parkia speciosa leaves has potential to be used as an antimicrobial agent against gram-positive bacteria Staphylococcus aureus more effectively than gram negative bacteria, Escherichia coli.
format	Thesis
qualification_level	Bachelor degree
author	Normila, Intan Alyani
author_facet	Normila, Intan Alyani
author_sort	Normila, Intan Alyani
title	The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila
title_short	The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila
title_full	The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila
title_fullStr	The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila
title_full_unstemmed	The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila
title_sort	assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / intan alyani normila
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Health Sciences
publishDate	2017
url	https://ir.uitm.edu.my/id/eprint/50140/1/50140.pdf
_version_	1783734821462212608

The assessment of efficacy of parkia speciosa leaves methanolic extract as an antimirobial agent / Intan Alyani Normila

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