Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi

Parkia speciosa or commonly known as ‘petai’ by locals is one of the famous plants that is abundantly found in Malaysia. The seeds are usually eaten raw (as ulam) or cooked (Lim, 2012). However, peels or pericarp is usually the waste part of the Parkia speciosa seed. The waste product has not genera...

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Main Author:	Azmi, Nor-Fatin Aina
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Food and food supply in relation to public health Drugs and their actions Fruit and fruit culture
Online Access:	https://ir.uitm.edu.my/id/eprint/50201/1/50201.pdf
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id	my-uitm-ir.50201
record_format	uketd_dc
spelling	my-uitm-ir.502012021-09-09T01:51:42Z Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi 2017 Azmi, Nor-Fatin Aina Food and food supply in relation to public health Drugs and their actions Fruit and fruit culture Parkia speciosa or commonly known as ‘petai’ by locals is one of the famous plants that is abundantly found in Malaysia. The seeds are usually eaten raw (as ulam) or cooked (Lim, 2012). However, peels or pericarp is usually the waste part of the Parkia speciosa seed. The waste product has not generally been given attention with a view to be used or recycled. Hence, the current study was initiated to identify the anticoagulant activity of the aqueous extract of the Parkia speciosa pericarp. Therefore, the proposed study started with the collection of 1 kg of fresh Parkia speciosa pericarp, cutting them into smaller pieces and drying them under the sun. The dried pericarp were then extracted by using the decoction method with distilled water as solvent. Activated partial thromboplastin time (aPTT), prothrombin time (PT) and thrombin time (TT) tests were performed on normal control plasma spiked with the different concentrations of the extract in duplicates. Finally, the clotting time were recorded and analysed using one-way ANOVA followed by post-hoc Dunnet’s test. aPTT and TT results obtained showed significant results (p < 0.05) at the highest concentration of extract which is was 100%. Contrary to aPTT and TT, no significant effect was observed for PT. Hence, the aqueous extract of Parkia speciosa pericarp was considered to possess anticoagulant effect which interfere with the extrinsic and common pathways. 2017 Thesis https://ir.uitm.edu.my/id/eprint/50201/ https://ir.uitm.edu.my/id/eprint/50201/1/50201.pdf text en public degree Universiti Teknologi Mara (Kampus Puncak Alam) Faculty of Information Management Mohamed, Emida
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Mohamed, Emida
topic	Food and food supply in relation to public health Drugs and their actions Fruit and fruit culture
spellingShingle	Food and food supply in relation to public health Drugs and their actions Fruit and fruit culture Azmi, Nor-Fatin Aina Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi
description	Parkia speciosa or commonly known as ‘petai’ by locals is one of the famous plants that is abundantly found in Malaysia. The seeds are usually eaten raw (as ulam) or cooked (Lim, 2012). However, peels or pericarp is usually the waste part of the Parkia speciosa seed. The waste product has not generally been given attention with a view to be used or recycled. Hence, the current study was initiated to identify the anticoagulant activity of the aqueous extract of the Parkia speciosa pericarp. Therefore, the proposed study started with the collection of 1 kg of fresh Parkia speciosa pericarp, cutting them into smaller pieces and drying them under the sun. The dried pericarp were then extracted by using the decoction method with distilled water as solvent. Activated partial thromboplastin time (aPTT), prothrombin time (PT) and thrombin time (TT) tests were performed on normal control plasma spiked with the different concentrations of the extract in duplicates. Finally, the clotting time were recorded and analysed using one-way ANOVA followed by post-hoc Dunnet’s test. aPTT and TT results obtained showed significant results (p < 0.05) at the highest concentration of extract which is was 100%. Contrary to aPTT and TT, no significant effect was observed for PT. Hence, the aqueous extract of Parkia speciosa pericarp was considered to possess anticoagulant effect which interfere with the extrinsic and common pathways.
format	Thesis
qualification_level	Bachelor degree
author	Azmi, Nor-Fatin Aina
author_facet	Azmi, Nor-Fatin Aina
author_sort	Azmi, Nor-Fatin Aina
title	Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi
title_short	Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi
title_full	Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi
title_fullStr	Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi
title_full_unstemmed	Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi
title_sort	screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / nor-fatin aina azmi
granting_institution	Universiti Teknologi Mara (Kampus Puncak Alam)
granting_department	Faculty of Information Management
publishDate	2017
url	https://ir.uitm.edu.my/id/eprint/50201/1/50201.pdf
_version_	1783734825193046016

Screening of anticoagulant activity from aqueous extract of parkia speciosa pericarp / Nor-Fatin Aina Azmi

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