The dombrock and indian blood group profiles among malays / Nur Amilin Azhan

The dombrock and indian blood group profiles among malays / Nur Amilin Azhan

Ethnic variations in red blood cell (RBC) antigens can be a source of alloimmunization, especially in-migrant populations. The differences in red blood cell antigen profiles between Malays and non-Malays may lead to blood incompatibility prior or during transfusion that may lead to various condition...

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Main Author: Azhan, Nur Amilin
Format: Thesis
Language:English
Published: 2017
Subjects:
Physical and theoretical chemistry
Immunology
Examination of the blood
Online Access:https://ir.uitm.edu.my/id/eprint/50212/1/50212.pdf
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id my-uitm-ir.50212
record_format uketd_dc
spelling my-uitm-ir.502122021-09-09T06:48:49Z The dombrock and indian blood group profiles among malays / Nur Amilin Azhan 2017 Azhan, Nur Amilin Physical and theoretical chemistry Immunology Examination of the blood Ethnic variations in red blood cell (RBC) antigens can be a source of alloimmunization, especially in-migrant populations. The differences in red blood cell antigen profiles between Malays and non-Malays may lead to blood incompatibility prior or during transfusion that may lead to various conditions and degrees of transfusion reaction. To improve transfusion safety in Malaysia, RBC genotyping to determine allele frequencies for high- and low-prevalence antigens was done. A total of 50 blood samples were collected from Malay students in UiTM Selangor, Malaysia. DNA was extracted and amplified using sequence specific primers-polymerase chain reaction (SSP-PCR) method. Results demonstrated that out of 50 subjects, 100% (50) were typed positive for DO*02 (DOB) and IN*02 (INB) while none of the subjects were typed (0%) for the antithetical allele, DO*01 (DOA) and IN*01 (INA), respectively. The findings demonstrated that the high frequency antigens among Malays are DOB and INB 2017 Thesis https://ir.uitm.edu.my/id/eprint/50212/ https://ir.uitm.edu.my/id/eprint/50212/1/50212.pdf text en public degree Universiti Teknologi Mara (Kampus Puncak Alam) Faculty of Health Sciences Bahari, Mazura
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Bahari, Mazura
topic Physical and theoretical chemistry
Immunology
Examination of the blood
spellingShingle Physical and theoretical chemistry
Immunology
Examination of the blood
Azhan, Nur Amilin
The dombrock and indian blood group profiles among malays / Nur Amilin Azhan
description Ethnic variations in red blood cell (RBC) antigens can be a source of alloimmunization, especially in-migrant populations. The differences in red blood cell antigen profiles between Malays and non-Malays may lead to blood incompatibility prior or during transfusion that may lead to various conditions and degrees of transfusion reaction. To improve transfusion safety in Malaysia, RBC genotyping to determine allele frequencies for high- and low-prevalence antigens was done. A total of 50 blood samples were collected from Malay students in UiTM Selangor, Malaysia. DNA was extracted and amplified using sequence specific primers-polymerase chain reaction (SSP-PCR) method. Results demonstrated that out of 50 subjects, 100% (50) were typed positive for DO*02 (DOB) and IN*02 (INB) while none of the subjects were typed (0%) for the antithetical allele, DO*01 (DOA) and IN*01 (INA), respectively. The findings demonstrated that the high frequency antigens among Malays are DOB and INB
format Thesis
qualification_level Bachelor degree
author Azhan, Nur Amilin
author_facet Azhan, Nur Amilin
author_sort Azhan, Nur Amilin
title The dombrock and indian blood group profiles among malays / Nur Amilin Azhan
title_short The dombrock and indian blood group profiles among malays / Nur Amilin Azhan
title_full The dombrock and indian blood group profiles among malays / Nur Amilin Azhan
title_fullStr The dombrock and indian blood group profiles among malays / Nur Amilin Azhan
title_full_unstemmed The dombrock and indian blood group profiles among malays / Nur Amilin Azhan
title_sort dombrock and indian blood group profiles among malays / nur amilin azhan
granting_institution Universiti Teknologi Mara (Kampus Puncak Alam)
granting_department Faculty of Health Sciences
publishDate 2017
url https://ir.uitm.edu.my/id/eprint/50212/1/50212.pdf
_version_ 1783734825978429440

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