Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail

Carica papaya (papaya) and Cucurbita maxima (pumpkin) have been used for treatment in many types of diseases for centuries. The crude aqueous extracts of both Carica papaya and Cucurbita maxima seeds were assayed synergistically against adult earthworms (Pheretima posthuma) for the evaluation of ant...

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Main Author:	Ismail, Nur Liyana
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Invertebrates Individual drugs and other agents Fruit and fruit culture
Online Access:	https://ir.uitm.edu.my/id/eprint/50232/1/50232.pdf
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id	my-uitm-ir.50232
record_format	uketd_dc
spelling	my-uitm-ir.502322021-09-09T07:50:36Z Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail 2017 Ismail, Nur Liyana Invertebrates Individual drugs and other agents Fruit and fruit culture Carica papaya (papaya) and Cucurbita maxima (pumpkin) have been used for treatment in many types of diseases for centuries. The crude aqueous extracts of both Carica papaya and Cucurbita maxima seeds were assayed synergistically against adult earthworms (Pheretima posthuma) for the evaluation of anthelminthic activity and compared with the standard drug, Albendazole. In this study, the traditional method was used; boiling and evaporation method. Various concentrations of the extracts and Albendazole were tested at 60 mg/ml, 40 mg/ml and 20 mg/ml. Six earthworms were immersed in three concentrations of each extracts; papaya-pumpkin seeds and Albendazole. Confirmation of paralysis was reported when decreased in movement after shaken vigorously. Death was recorded after ascertaining that the worms neither moved when shaken vigorously nor dipped in warm water of 50oC. Results were expressed in terms of time for paralysis (P) and death time (D) of worms using mean SD and data analysis by One-way Anova. Interestingly, the time of death for worms showed that the crude aqueous extracts of seeds at concentration of 20 mg/ml could totally exterminate the worm at the shortest time (111.50 ± 4.95) compared to Albendazole (112.50 ± 4.96). In conclusion, the combination of Carica papaya and Cucurbita maxima is a good option to be taken as an alternative medicine in treating cases of intestinal worm infections. 2017 Thesis https://ir.uitm.edu.my/id/eprint/50232/ https://ir.uitm.edu.my/id/eprint/50232/1/50232.pdf text en public degree Universiti Teknologi Mara (Kampus Puncak Alam) Faculty of Health Sciences Yusof, Hartini
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Yusof, Hartini
topic	Invertebrates Individual drugs and other agents Fruit and fruit culture
spellingShingle	Invertebrates Individual drugs and other agents Fruit and fruit culture Ismail, Nur Liyana Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
description	Carica papaya (papaya) and Cucurbita maxima (pumpkin) have been used for treatment in many types of diseases for centuries. The crude aqueous extracts of both Carica papaya and Cucurbita maxima seeds were assayed synergistically against adult earthworms (Pheretima posthuma) for the evaluation of anthelminthic activity and compared with the standard drug, Albendazole. In this study, the traditional method was used; boiling and evaporation method. Various concentrations of the extracts and Albendazole were tested at 60 mg/ml, 40 mg/ml and 20 mg/ml. Six earthworms were immersed in three concentrations of each extracts; papaya-pumpkin seeds and Albendazole. Confirmation of paralysis was reported when decreased in movement after shaken vigorously. Death was recorded after ascertaining that the worms neither moved when shaken vigorously nor dipped in warm water of 50oC. Results were expressed in terms of time for paralysis (P) and death time (D) of worms using mean SD and data analysis by One-way Anova. Interestingly, the time of death for worms showed that the crude aqueous extracts of seeds at concentration of 20 mg/ml could totally exterminate the worm at the shortest time (111.50 ± 4.95) compared to Albendazole (112.50 ± 4.96). In conclusion, the combination of Carica papaya and Cucurbita maxima is a good option to be taken as an alternative medicine in treating cases of intestinal worm infections.
format	Thesis
qualification_level	Bachelor degree
author	Ismail, Nur Liyana
author_facet	Ismail, Nur Liyana
author_sort	Ismail, Nur Liyana
title	Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_short	Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_full	Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_fullStr	Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_full_unstemmed	Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail
title_sort	investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / nur liyana ismail
granting_institution	Universiti Teknologi Mara (Kampus Puncak Alam)
granting_department	Faculty of Health Sciences
publishDate	2017
url	https://ir.uitm.edu.my/id/eprint/50232/1/50232.pdf
_version_	1783734827813437440

Investigation of synergistic anthelmintic potential of papaya-pumpkin seeds against earthworm (pheretima posthuma) / Nur Liyana Ismail

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