Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan

Andrographis paniculata which is also known as “Kind of Bitter” (English) or Hempedu Bumi (Malay) belongs to the family Acanthaceae which is an important medical plant that has been widely used in southern Asia to treat infections and other diseases. A. paniculata has been used as antibiotic, antivi...

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Main Author:	Tan, Nur Nabilah
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Cryptogams Drugs and their actions Medicinal plants (Culture only)
Online Access:	https://ir.uitm.edu.my/id/eprint/50234/1/50234.pdf
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id	my-uitm-ir.50234
record_format	uketd_dc
spelling	my-uitm-ir.502342021-09-09T08:00:21Z Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan 2017 Tan, Nur Nabilah Cryptogams Drugs and their actions Medicinal plants (Culture only) Andrographis paniculata which is also known as “Kind of Bitter” (English) or Hempedu Bumi (Malay) belongs to the family Acanthaceae which is an important medical plant that has been widely used in southern Asia to treat infections and other diseases. A. paniculata has been used as antibiotic, antiviral, antimicrobial, antiinflammatory, anticancer, anti-HIV and anti-allergic agent. A. paniculata leaves was collected and authentication was performed. Leaves were extracted with methanol. The fungus samples was collected from moldy bread and cultured on Sabouraud Dextrose agar (SDA). The fungal isolated was identified through macroscopic and microscopic characteristics. The antifungal assay was performed using the disc diffusion method by tested the isolated against different concentration of methanolic extract of Andrographis paniculata leaves at 1000, 500, 250, 125, 62.5 and 31.25 mg/ml respectively. Based on the macroscopic and microscopic characteristics, it was suggested that the isolated fungus is presumptively identified as Penicillium species. There was no inhibition zone observed when different concentrations of methanolic extract of Andrograophis paniculata leaves were used within study tested against the isolated fungus. Based on this study, the isolated fungus from moldy bread was presumptively identified as Penicillium specices and all the different concentrations of methanolic extracts of Andrographis paniculata did not show any inhibitory effects towards isolated fungus. 2017 Thesis https://ir.uitm.edu.my/id/eprint/50234/ https://ir.uitm.edu.my/id/eprint/50234/1/50234.pdf text en public phd doctoral Universiti Teknologi Mara (Kampus Puncak Alam) Faculty of Health Sciences Mohamad Hussain, Roslinah
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Mohamad Hussain, Roslinah
topic	Cryptogams Drugs and their actions Medicinal plants (Culture only)
spellingShingle	Cryptogams Drugs and their actions Medicinal plants (Culture only) Tan, Nur Nabilah Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan
description	Andrographis paniculata which is also known as “Kind of Bitter” (English) or Hempedu Bumi (Malay) belongs to the family Acanthaceae which is an important medical plant that has been widely used in southern Asia to treat infections and other diseases. A. paniculata has been used as antibiotic, antiviral, antimicrobial, antiinflammatory, anticancer, anti-HIV and anti-allergic agent. A. paniculata leaves was collected and authentication was performed. Leaves were extracted with methanol. The fungus samples was collected from moldy bread and cultured on Sabouraud Dextrose agar (SDA). The fungal isolated was identified through macroscopic and microscopic characteristics. The antifungal assay was performed using the disc diffusion method by tested the isolated against different concentration of methanolic extract of Andrographis paniculata leaves at 1000, 500, 250, 125, 62.5 and 31.25 mg/ml respectively. Based on the macroscopic and microscopic characteristics, it was suggested that the isolated fungus is presumptively identified as Penicillium species. There was no inhibition zone observed when different concentrations of methanolic extract of Andrograophis paniculata leaves were used within study tested against the isolated fungus. Based on this study, the isolated fungus from moldy bread was presumptively identified as Penicillium specices and all the different concentrations of methanolic extracts of Andrographis paniculata did not show any inhibitory effects towards isolated fungus.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Tan, Nur Nabilah
author_facet	Tan, Nur Nabilah
author_sort	Tan, Nur Nabilah
title	Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan
title_short	Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan
title_full	Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan
title_fullStr	Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan
title_full_unstemmed	Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan
title_sort	determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / nur nabilah tan
granting_institution	Universiti Teknologi Mara (Kampus Puncak Alam)
granting_department	Faculty of Health Sciences
publishDate	2017
url	https://ir.uitm.edu.my/id/eprint/50234/1/50234.pdf
_version_	1783734828061949952

Determination of potential antifungal activity of methanolic extract of andrographis paniculata leaves against isolated fungus from moldy bread / Nur Nabilah Tan

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