The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof

This present study is about the antigen and phenotype blood group systems that have high frequency antigen in Malays. The Colton and Lutheran blood group is an unknown blood group system. These blood groups are important because they can lead to hemolytic transfusion reaction and autoimmune hemolyti...

Full description

Saved in:

Bibliographic Details
Main Author:	Yusof, Siti Zulaikha
Format:	Thesis
Language:	English
Published:	2017
Subjects:	Organic chemistry Immunology Biomedical engineering
Online Access:	https://ir.uitm.edu.my/id/eprint/50370/1/50370.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-uitm-ir.50370
record_format	uketd_dc
spelling	my-uitm-ir.503702021-09-13T02:43:45Z The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof 2017 Yusof, Siti Zulaikha Organic chemistry Immunology Biomedical engineering This present study is about the antigen and phenotype blood group systems that have high frequency antigen in Malays. The Colton and Lutheran blood group is an unknown blood group system. These blood groups are important because they can lead to hemolytic transfusion reaction and autoimmune hemolytic anemia. Although ABO and Rhesus have been extensively study in this population, the data distribution of Colton and Lutheran blood group remains largely unknown. Therefore, we analyzed the frequency of less explored blood group using DNA based assay and interpret these data in the view of population. Polymorphisms of Colton and Lutheran blood group were collected from samples of 50 Malays voluntary Medical Laboratory UITM Puncak Alam Campus undergraduate students using sequences specific primer PCRSSP methods for typing PCR product of blood group antigen (Coa, Cob, Lu8, Lu14). Result shown that, in the Lutheran blood group the most common phenotype among Malays was Lu8 14% (7/50). Lu8 antigen was seen in 6% (3/50) and 8% (4/50) of male and female respectively. The other phenotypes shown that no positive results for specific allele tested. 2017 Thesis https://ir.uitm.edu.my/id/eprint/50370/ https://ir.uitm.edu.my/id/eprint/50370/1/50370.pdf text en public degree Universiti Teknologi MARA ( Kampus Puncak Alam ) Faculty of Health Sciences Bahari, Mazura
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Bahari, Mazura
topic	Organic chemistry Immunology Biomedical engineering
spellingShingle	Organic chemistry Immunology Biomedical engineering Yusof, Siti Zulaikha The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof
description	This present study is about the antigen and phenotype blood group systems that have high frequency antigen in Malays. The Colton and Lutheran blood group is an unknown blood group system. These blood groups are important because they can lead to hemolytic transfusion reaction and autoimmune hemolytic anemia. Although ABO and Rhesus have been extensively study in this population, the data distribution of Colton and Lutheran blood group remains largely unknown. Therefore, we analyzed the frequency of less explored blood group using DNA based assay and interpret these data in the view of population. Polymorphisms of Colton and Lutheran blood group were collected from samples of 50 Malays voluntary Medical Laboratory UITM Puncak Alam Campus undergraduate students using sequences specific primer PCRSSP methods for typing PCR product of blood group antigen (Coa, Cob, Lu8, Lu14). Result shown that, in the Lutheran blood group the most common phenotype among Malays was Lu8 14% (7/50). Lu8 antigen was seen in 6% (3/50) and 8% (4/50) of male and female respectively. The other phenotypes shown that no positive results for specific allele tested.
format	Thesis
qualification_level	Bachelor degree
author	Yusof, Siti Zulaikha
author_facet	Yusof, Siti Zulaikha
author_sort	Yusof, Siti Zulaikha
title	The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof
title_short	The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof
title_full	The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof
title_fullStr	The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof
title_full_unstemmed	The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof
title_sort	prevalence of colton and lutheran blood profiles among malays / siti zulaikha yusof
granting_institution	Universiti Teknologi MARA ( Kampus Puncak Alam )
granting_department	Faculty of Health Sciences
publishDate	2017
url	https://ir.uitm.edu.my/id/eprint/50370/1/50370.pdf
_version_	1783734832372645888

The prevalence of Colton and Lutheran blood profiles among Malays / Siti Zulaikha Yusof

Similar Items