Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli

Blood group O is known as universal donors. However, some of the antibodies which are anti A and anti B, may cause hemolysis of red blood cells recipient’s if present in sufficient high titer. Therefore, this pilot study was conducted to determine the prevalence of anti A and anti B titer among the...

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Main Author: Mohd Azli, Alia Maisarah
Format: Thesis
Language:English
Published: 2019
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Online Access:https://ir.uitm.edu.my/id/eprint/51078/1/51078.pdf
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spelling my-uitm-ir.510782021-09-28T08:25:52Z Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli 2019 Mohd Azli, Alia Maisarah Examination of the blood Administration Blood group O is known as universal donors. However, some of the antibodies which are anti A and anti B, may cause hemolysis of red blood cells recipient’s if present in sufficient high titer. Therefore, this pilot study was conducted to determine the prevalence of anti A and anti B titer among the blood group O donors. This study was carried out on 30 originated from leftover samples. All the samples from blood group O donors had been chosen randomly. Anti A and anti B antibody titration using the conventional tube technique had been done. Pearson Chi-square and Fisher’s Exact test was used to compare the association between titration value and types of antibody. This study showed that the prevalence of anti A and anti B titer among blood group O donors is 90.0% at the titer lower than 128. Moreover, the critical value of ‘high-titer’ is also at the titer lower than 128. The result showed that there is no significance association between titration value and types of antibody (p > 0.05). In conclusion, the blood group O donors can be accepted as the universal donors and can be released as safe O when the titer is lower than 128. 2019 Thesis https://ir.uitm.edu.my/id/eprint/51078/ https://ir.uitm.edu.my/id/eprint/51078/1/51078.pdf text en public degree Universiti Teknologi MARA ( Kampus Puncak Alam ) Faculty of Health Sciences Bahari, Mazura
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Bahari, Mazura
topic Examination of the blood
Administration
spellingShingle Examination of the blood
Administration
Mohd Azli, Alia Maisarah
Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli
description Blood group O is known as universal donors. However, some of the antibodies which are anti A and anti B, may cause hemolysis of red blood cells recipient’s if present in sufficient high titer. Therefore, this pilot study was conducted to determine the prevalence of anti A and anti B titer among the blood group O donors. This study was carried out on 30 originated from leftover samples. All the samples from blood group O donors had been chosen randomly. Anti A and anti B antibody titration using the conventional tube technique had been done. Pearson Chi-square and Fisher’s Exact test was used to compare the association between titration value and types of antibody. This study showed that the prevalence of anti A and anti B titer among blood group O donors is 90.0% at the titer lower than 128. Moreover, the critical value of ‘high-titer’ is also at the titer lower than 128. The result showed that there is no significance association between titration value and types of antibody (p > 0.05). In conclusion, the blood group O donors can be accepted as the universal donors and can be released as safe O when the titer is lower than 128.
format Thesis
qualification_level Bachelor degree
author Mohd Azli, Alia Maisarah
author_facet Mohd Azli, Alia Maisarah
author_sort Mohd Azli, Alia Maisarah
title Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli
title_short Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli
title_full Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli
title_fullStr Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli
title_full_unstemmed Prevalence of anti A and anti B titer among blood group O donors / Alia Maisarah Mohd Azli
title_sort prevalence of anti a and anti b titer among blood group o donors / alia maisarah mohd azli
granting_institution Universiti Teknologi MARA ( Kampus Puncak Alam )
granting_department Faculty of Health Sciences
publishDate 2019
url https://ir.uitm.edu.my/id/eprint/51078/1/51078.pdf
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