Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh

Objective: The main purpose of this study is determine the pain score profile of patients prescribed with analgesic using the Short Form McGill Pain Questionnaire and to assess the use of analgesic drugs in orthopedic post operative patients is appropriate. Method : A cross sectional study was condu...

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Main Author:	Mat Salleh, Khairul Barriah
Format:	Thesis
Language:	English
Published:	2012
Subjects:	Pharmaceutical dosage forms
Online Access:	https://ir.uitm.edu.my/id/eprint/54179/1/54179.pdf
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spelling	my-uitm-ir.541792022-01-04T09:22:04Z Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh 2012 Mat Salleh, Khairul Barriah Pharmaceutical dosage forms Commercial preparations. Patent medicines Objective: The main purpose of this study is determine the pain score profile of patients prescribed with analgesic using the Short Form McGill Pain Questionnaire and to assess the use of analgesic drugs in orthopedic post operative patients is appropriate. Method : A cross sectional study was conducted on 102 patients undergoing orthopaedic surgeries in Hospital Kajang, Selangor. The data was collected between August and November 2011. Data collection was carried out using the Short-Form McGill Pain Questionnaire (SF-MPQ). Patients pain score was measured using VAS pain score (1 to 10), on day 1 of operation (Dl), day 3 (D3) and on last day of treatment (DL). Descriptive statistics were used to describe demographic data. Pearson Chi-square was used for all categorical data. The Independent T-test was applied to compare mean pain score with two categorical variables. One-way analysis of variance (ANOVA) was used to compare mean pain score with categorical variables of more than 2 groups. For the cost of medications taken by patients during their hospitalization, Spearman's Rho Correlation Coefficient was used to see the correlation between drug costs and pain score with other numerical variables. Repeated Measure ANOVA was used to investigate the pattern or changes in pain score from day 1(D1) to last day of treatment (DL) in different categorical variables. Mean and standard deviations value for Sensory and Affective Descriptors was also calculated. A p value of <0.05 was considered statistically significant with a confidence interval of 95%. Results: This study found that the mean difference between the 3 days after operation was significantly different (p <0.001). The mean pain score was 6:52 ±2:18 on Dl, 3.72 ± 1.69 on D3 and 0.93 ± 0.85 on DL of treatment respectively. There were no significant difference in total pain score between male (133.37± 93.23) and female patients (158.94± 77.20). Further analysis with Repeated Measure ANOVA found a significant reduction (p<0.05) of pain score between male and female (p=0.0109) on Dl to DL. There was a significant reduction (p<0.05) of pain score between duration of treatment (p=0.016) on Dl to DL. There was also a low, positive correlation between Analgesia Drug Cost and Patients' Pain Score(r = 0.311, n = 102, P = 0.001), Analgesia Cost and Duration of Treatment (r = 0.468, n = 102, P - < 0.001) and Analgesia Cost and Duration of Operation (r = 0.383, n = 102, P = < 0.001). Conclusions: This study found that there was a significant reduction in pain levels of patients from Dl to DL after surgery. This illustrates that the use of proper medication can produce positive outcome. The selection of appropriate drugs is important to ensure the effectiveness of treatment, to achieve patient satisfaction and to reduce side effects of drugs and complications after surgery. 2012 Thesis https://ir.uitm.edu.my/id/eprint/54179/ https://ir.uitm.edu.my/id/eprint/54179/1/54179.pdf text en public masters Universiti Teknologi MARA Faculty of Pharmacy
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
topic	Pharmaceutical dosage forms Pharmaceutical dosage forms
spellingShingle	Pharmaceutical dosage forms Pharmaceutical dosage forms Mat Salleh, Khairul Barriah Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh
description	Objective: The main purpose of this study is determine the pain score profile of patients prescribed with analgesic using the Short Form McGill Pain Questionnaire and to assess the use of analgesic drugs in orthopedic post operative patients is appropriate. Method : A cross sectional study was conducted on 102 patients undergoing orthopaedic surgeries in Hospital Kajang, Selangor. The data was collected between August and November 2011. Data collection was carried out using the Short-Form McGill Pain Questionnaire (SF-MPQ). Patients pain score was measured using VAS pain score (1 to 10), on day 1 of operation (Dl), day 3 (D3) and on last day of treatment (DL). Descriptive statistics were used to describe demographic data. Pearson Chi-square was used for all categorical data. The Independent T-test was applied to compare mean pain score with two categorical variables. One-way analysis of variance (ANOVA) was used to compare mean pain score with categorical variables of more than 2 groups. For the cost of medications taken by patients during their hospitalization, Spearman's Rho Correlation Coefficient was used to see the correlation between drug costs and pain score with other numerical variables. Repeated Measure ANOVA was used to investigate the pattern or changes in pain score from day 1(D1) to last day of treatment (DL) in different categorical variables. Mean and standard deviations value for Sensory and Affective Descriptors was also calculated. A p value of <0.05 was considered statistically significant with a confidence interval of 95%. Results: This study found that the mean difference between the 3 days after operation was significantly different (p <0.001). The mean pain score was 6:52 ±2:18 on Dl, 3.72 ± 1.69 on D3 and 0.93 ± 0.85 on DL of treatment respectively. There were no significant difference in total pain score between male (133.37± 93.23) and female patients (158.94± 77.20). Further analysis with Repeated Measure ANOVA found a significant reduction (p<0.05) of pain score between male and female (p=0.0109) on Dl to DL. There was a significant reduction (p<0.05) of pain score between duration of treatment (p=0.016) on Dl to DL. There was also a low, positive correlation between Analgesia Drug Cost and Patients' Pain Score(r = 0.311, n = 102, P = 0.001), Analgesia Cost and Duration of Treatment (r = 0.468, n = 102, P - < 0.001) and Analgesia Cost and Duration of Operation (r = 0.383, n = 102, P = < 0.001). Conclusions: This study found that there was a significant reduction in pain levels of patients from Dl to DL after surgery. This illustrates that the use of proper medication can produce positive outcome. The selection of appropriate drugs is important to ensure the effectiveness of treatment, to achieve patient satisfaction and to reduce side effects of drugs and complications after surgery.
format	Thesis
qualification_level	Master's degree
author	Mat Salleh, Khairul Barriah
author_facet	Mat Salleh, Khairul Barriah
author_sort	Mat Salleh, Khairul Barriah
title	Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh
title_short	Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh
title_full	Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh
title_fullStr	Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh
title_full_unstemmed	Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh
title_sort	evaluation of analgesic use in orthopaedic postoperative acute pain management / khairul barriah mat salleh
granting_institution	Universiti Teknologi MARA
granting_department	Faculty of Pharmacy
publishDate	2012
url	https://ir.uitm.edu.my/id/eprint/54179/1/54179.pdf
_version_	1783734888794423296

Evaluation of analgesic use in orthopaedic postoperative acute pain management / Khairul Barriah Mat Salleh

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