Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin
Menopause is a permanent cessation that occurs in women in Malaysia is between 45 to 55 years old. It is often associated with increased body weight and body fat distribution due to the deprivation of estrogen hormone. Labisia pumila is an herbal plant that Malaysian women widely consume as a her...
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my-uitm-ir.601842022-05-24T02:18:31Z Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin 2021-05 Kamaludin, Siti Nuraida RG Gynecology and obstetrics Herbs. Herbal teas Menopause is a permanent cessation that occurs in women in Malaysia is between 45 to 55 years old. It is often associated with increased body weight and body fat distribution due to the deprivation of estrogen hormone. Labisia pumila is an herbal plant that Malaysian women widely consume as a herbal tonic. This herb helps in regulating menstruation, feminine vitality and hormonal imbalance. It is speculated to exhibit phytoestrogenic activity that has similar structures to estrogen hormone. This study was conducted to determine the antioxidant activities i.e., total phenolic and flavonoids; and the present of polyphenols compound in commercially produced L. pumila aqueous extract with excipients (LPE). The study also aimed to assess the acute and subacute oral toxicity studies; and to evaluate the effects of supplementation of the LPE on body weight changes, female reproductive hormone (estradiol, folliclestimulating hormone, and luteinizing hormone) and metabolic disease marker (glucose, insulin, adiponectin, leptin, and resistin) of menopause induced rats. 2021-05 Thesis https://ir.uitm.edu.my/id/eprint/60184/ https://ir.uitm.edu.my/id/eprint/60184/1/60184.pdf text en public masters Universiti Teknologi MARA Faculty of Pharmacy Eshak, Zolkapli (Dr.) |
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Universiti Teknologi MARA |
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UiTM Institutional Repository |
| language |
English |
| advisor |
Eshak, Zolkapli (Dr.) |
| topic |
RG Gynecology and obstetrics RG Gynecology and obstetrics |
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RG Gynecology and obstetrics RG Gynecology and obstetrics Kamaludin, Siti Nuraida Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin |
| description |
Menopause is a permanent cessation that occurs in women in Malaysia is between 45
to 55 years old. It is often associated with increased body weight and body fat
distribution due to the deprivation of estrogen hormone. Labisia pumila is an herbal
plant that Malaysian women widely consume as a herbal tonic. This herb helps in
regulating menstruation, feminine vitality and hormonal imbalance. It is speculated to
exhibit phytoestrogenic activity that has similar structures to estrogen hormone. This
study was conducted to determine the antioxidant activities i.e., total phenolic and
flavonoids; and the present of polyphenols compound in commercially produced L.
pumila aqueous extract with excipients (LPE). The study also aimed to assess the acute
and subacute oral toxicity studies; and to evaluate the effects of supplementation of the
LPE on body weight changes, female reproductive hormone (estradiol, folliclestimulating
hormone, and luteinizing hormone) and metabolic disease marker (glucose,
insulin, adiponectin, leptin, and resistin) of menopause induced rats. |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Kamaludin, Siti Nuraida |
| author_facet |
Kamaludin, Siti Nuraida |
| author_sort |
Kamaludin, Siti Nuraida |
| title |
Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin |
| title_short |
Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin |
| title_full |
Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin |
| title_fullStr |
Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin |
| title_full_unstemmed |
Effect of Labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / Siti Nuraida Kamaludin |
| title_sort |
effect of labisia pumila aqueous extract on the estrogenic activity and metabolic disease markers in bilateral ovariectomized rats / siti nuraida kamaludin |
| granting_institution |
Universiti Teknologi MARA |
| granting_department |
Faculty of Pharmacy |
| publishDate |
2021 |
| url |
https://ir.uitm.edu.my/id/eprint/60184/1/60184.pdf |
| _version_ |
1783735096782618624 |