Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli

Population aging is pervasive. It is estimated that in 2010 the percentage of elderly population is around 7% and this percentage is expected to increase to 10% in 2020. A high proportion of this population is having cardiovascular diseases and therefore is frequent users of cardiovascular medicatio...

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Main Author:	Rusli, Nur Asyikin
Format:	Thesis
Language:	English
Published:	2012
Subjects:	Computer applications to medicine Medical informatics Diseases of the circulatory (Cardiovascular) system
Online Access:	https://ir.uitm.edu.my/id/eprint/65555/1/65555.pdf
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id	my-uitm-ir.65555
record_format	uketd_dc
spelling	my-uitm-ir.655552022-08-23T02:02:50Z Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli 2012 Rusli, Nur Asyikin Computer applications to medicine. Medical informatics Medical centers. Hospitals. Dispensaries. Clinics Diseases of the circulatory (Cardiovascular) system Population aging is pervasive. It is estimated that in 2010 the percentage of elderly population is around 7% and this percentage is expected to increase to 10% in 2020. A high proportion of this population is having cardiovascular diseases and therefore is frequent users of cardiovascular medications. Due to age-related physiological changes, the elderly react differently to medications as compared to younger patients. Changes in the pharmacokinetics and pharmacodynamics of drugs among the elderly predispose them to ADR. This study aims to detect the prevalence of potentially inappropriate cardiovascular medications (PICM) among a group of elderly patients admitted into a government hospital and to identify the most frequent PICM use among them by using the Screening Tool of Older Patient’s Prescriptions (STOPP). Medications records of 143 elderly patients of ≥ 65 years were prospectively studied to determine the prevalence and the frequency of PICM among them. The total amount of medications evaluated was 815; mean number of medications per patient was 5.7 ± 3.3. Overall the STOPP criteria detected 43 PICMs in 26.6% of patients. The most frequent encountered PICM was calcium channel blocker with chronic constipation (17.5%), aspirin, clopidogrel, dipyridamole or warfarin with concurrent bleeding disorders (5.6%) and loop diuretics for dependent ankle edema with no clinical sign of heart failure (2.8%). PICM use is highly preventable. Measures to reduce PICM use among elderly patients should be undertaken by the pharmacists and physicians. The applicability and utility of the STOPP criteria at local government hospitals should be studied further. 2012 Thesis https://ir.uitm.edu.my/id/eprint/65555/ https://ir.uitm.edu.my/id/eprint/65555/1/65555.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Abdul Wahab, Mohd Shahezwan
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Abdul Wahab, Mohd Shahezwan
topic	Computer applications to medicine Medical informatics Computer applications to medicine Medical informatics Diseases of the circulatory (Cardiovascular) system
spellingShingle	Computer applications to medicine Medical informatics Computer applications to medicine Medical informatics Diseases of the circulatory (Cardiovascular) system Rusli, Nur Asyikin Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli
description	Population aging is pervasive. It is estimated that in 2010 the percentage of elderly population is around 7% and this percentage is expected to increase to 10% in 2020. A high proportion of this population is having cardiovascular diseases and therefore is frequent users of cardiovascular medications. Due to age-related physiological changes, the elderly react differently to medications as compared to younger patients. Changes in the pharmacokinetics and pharmacodynamics of drugs among the elderly predispose them to ADR. This study aims to detect the prevalence of potentially inappropriate cardiovascular medications (PICM) among a group of elderly patients admitted into a government hospital and to identify the most frequent PICM use among them by using the Screening Tool of Older Patient’s Prescriptions (STOPP). Medications records of 143 elderly patients of ≥ 65 years were prospectively studied to determine the prevalence and the frequency of PICM among them. The total amount of medications evaluated was 815; mean number of medications per patient was 5.7 ± 3.3. Overall the STOPP criteria detected 43 PICMs in 26.6% of patients. The most frequent encountered PICM was calcium channel blocker with chronic constipation (17.5%), aspirin, clopidogrel, dipyridamole or warfarin with concurrent bleeding disorders (5.6%) and loop diuretics for dependent ankle edema with no clinical sign of heart failure (2.8%). PICM use is highly preventable. Measures to reduce PICM use among elderly patients should be undertaken by the pharmacists and physicians. The applicability and utility of the STOPP criteria at local government hospitals should be studied further.
format	Thesis
qualification_level	Bachelor degree
author	Rusli, Nur Asyikin
author_facet	Rusli, Nur Asyikin
author_sort	Rusli, Nur Asyikin
title	Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli
title_short	Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli
title_full	Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli
title_fullStr	Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli
title_full_unstemmed	Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli
title_sort	evaluation of potentially inappropriate cardiovascular medication use as determined by the stopp criteria among elderly inpatients admitted in hospital selayang / nur asyikin rusli
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Pharmacy
publishDate	2012
url	https://ir.uitm.edu.my/id/eprint/65555/1/65555.pdf
_version_	1783735557932711936

Evaluation of potentially inappropriate cardiovascular medication use as determined by the STOPP criteria among elderly inpatients admitted in Hospital Selayang / Nur Asyikin Rusli

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