Docking of mouse p-glycoprotein (ABCB1a/MDR3) with Rhodamine B and Vinblastine / Hazureen Mohd Halimi
P-glycoprotein (Pgp) is an ATP-dependent transport protein that is selectively expressed at entry points of xenobiotics. It acts as an efflux pump that prevents xenobiotics from entering sensitive organs. Pgp also plays a key role in the absorption and blood-brain barrier penetration of many drugs....
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Main Author: | Mohd Halimi, Hazureen |
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Format: | Thesis |
Language: | English |
Published: |
2012
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Subjects: | |
Online Access: | https://ir.uitm.edu.my/id/eprint/66678/1/66678.pdf |
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