Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff
The present study envisaged studying the combined effect of co-solvent and surfactant and the resultant solubility enhancement of drug Naproxen by volumetric and acoustical studies. Highest solubilization was achieved in the mixed solvent systems containing 0.8%w/v of sodium dodecyl sulfate and 8% o...
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2012
|
| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/66705/1/66705.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
my-uitm-ir.66705 |
|---|---|
| record_format |
uketd_dc |
| spelling |
my-uitm-ir.667052022-09-14T03:20:43Z Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff 2012 Yusoff, Noor Adilah Drugs and their actions The present study envisaged studying the combined effect of co-solvent and surfactant and the resultant solubility enhancement of drug Naproxen by volumetric and acoustical studies. Highest solubilization was achieved in the mixed solvent systems containing 0.8%w/v of sodium dodecyl sulfate and 8% of ethanol. The densities and the ultrasonic sound velocity datas obtained are duly treated so to find out the thermophysical parameters. The solubility data (presented elsewhere) are well correlated with the findings of the thermophysical parameters related to volumetric and acoustic studies. The most favourable environment as per the volumetric and acoustical analysis being characterized by a strong solute solvent interaction, open packing, less electrostriction, increased isentropic compressibility and decreased internal pressure. 2012 Thesis https://ir.uitm.edu.my/id/eprint/66705/ https://ir.uitm.edu.my/id/eprint/66705/1/66705.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Tripathy, Minaketan |
| institution |
Universiti Teknologi MARA |
| collection |
UiTM Institutional Repository |
| language |
English |
| advisor |
Tripathy, Minaketan |
| topic |
Drugs and their actions |
| spellingShingle |
Drugs and their actions Yusoff, Noor Adilah Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff |
| description |
The present study envisaged studying the combined effect of co-solvent and surfactant and the resultant solubility enhancement of drug Naproxen by volumetric and acoustical studies. Highest solubilization was achieved in the mixed solvent systems containing 0.8%w/v of sodium dodecyl sulfate and 8% of ethanol. The densities and the ultrasonic sound velocity datas obtained are duly treated so to find out the thermophysical parameters. The solubility data (presented elsewhere) are well correlated with the findings of the thermophysical parameters related to volumetric and acoustic studies. The most favourable environment as per the volumetric and acoustical analysis being characterized by a strong solute solvent interaction, open packing, less electrostriction, increased isentropic compressibility and decreased internal pressure. |
| format |
Thesis |
| qualification_level |
Bachelor degree |
| author |
Yusoff, Noor Adilah |
| author_facet |
Yusoff, Noor Adilah |
| author_sort |
Yusoff, Noor Adilah |
| title |
Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff |
| title_short |
Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff |
| title_full |
Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff |
| title_fullStr |
Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff |
| title_full_unstemmed |
Combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / Noor Adilah Yusoff |
| title_sort |
combined effect of co-solvent and surfactant, upon the solubility of naproxen: volumetric and acoustic studies / noor adilah yusoff |
| granting_institution |
Universiti Teknologi MARA (UiTM) |
| granting_department |
Faculty of Pharmacy |
| publishDate |
2012 |
| url |
https://ir.uitm.edu.my/id/eprint/66705/1/66705.pdf |
| _version_ |
1783735634418991104 |