Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani

Ant plants or Sarang Semut tubers are alternative medicinal plants which have been increasingly used traditionally for a broad range of therapeutic values. The purpose of this study was to investigate the potency of Myrmecodia platytyrea species of ant plants, as immunomodulator by evaluating its ef...

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Main Author:	Jailani, Norwati
Format:	Thesis
Language:	English
Published:	2012
Subjects:	Immune response
Online Access:	https://ir.uitm.edu.my/id/eprint/66747/1/66747.pdf
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id	my-uitm-ir.66747
record_format	uketd_dc
spelling	my-uitm-ir.667472022-09-15T01:32:02Z Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani 2012 Jailani, Norwati Immune response Herbs. Herbal teas Ant plants or Sarang Semut tubers are alternative medicinal plants which have been increasingly used traditionally for a broad range of therapeutic values. The purpose of this study was to investigate the potency of Myrmecodia platytyrea species of ant plants, as immunomodulator by evaluating its effect on lymphocytes subpopulations. In this study, group I was designed as vehicle control while rats in each group II, III and IV, were administered with different dose of extract solution for 14 days. Methanol extract of Myrmecodia platytyrea was made to solution with concentrations of 100, 200 and 400 mg/kg by adding 0.9% normal saline. Lymphocytes subpopulations analysis was carried out by using the flow cytometry analysis. The study demonstrated that Myrmecodia platytyrea tuber increased the percentages of lymphocytes subpopulations as compared to the vehicle control, with the higher immunostimulatory effects have shown by group II (100 mg/kg), followed by group III (200 mg/kg), and the lower effects have exerted by group IV (400 mg/kg). Overall, the results showed that Myrmecodia platytyrea tuber has potential to be developed as immunomodulatory agent. 2012 Thesis https://ir.uitm.edu.my/id/eprint/66747/ https://ir.uitm.edu.my/id/eprint/66747/1/66747.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Mahamood, Maziana
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Mahamood, Maziana
topic	Immune response Immune response
spellingShingle	Immune response Immune response Jailani, Norwati Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani
description	Ant plants or Sarang Semut tubers are alternative medicinal plants which have been increasingly used traditionally for a broad range of therapeutic values. The purpose of this study was to investigate the potency of Myrmecodia platytyrea species of ant plants, as immunomodulator by evaluating its effect on lymphocytes subpopulations. In this study, group I was designed as vehicle control while rats in each group II, III and IV, were administered with different dose of extract solution for 14 days. Methanol extract of Myrmecodia platytyrea was made to solution with concentrations of 100, 200 and 400 mg/kg by adding 0.9% normal saline. Lymphocytes subpopulations analysis was carried out by using the flow cytometry analysis. The study demonstrated that Myrmecodia platytyrea tuber increased the percentages of lymphocytes subpopulations as compared to the vehicle control, with the higher immunostimulatory effects have shown by group II (100 mg/kg), followed by group III (200 mg/kg), and the lower effects have exerted by group IV (400 mg/kg). Overall, the results showed that Myrmecodia platytyrea tuber has potential to be developed as immunomodulatory agent.
format	Thesis
qualification_level	Bachelor degree
author	Jailani, Norwati
author_facet	Jailani, Norwati
author_sort	Jailani, Norwati
title	Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani
title_short	Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani
title_full	Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani
title_fullStr	Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani
title_full_unstemmed	Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani
title_sort	study of the effects of myrmecodia platytyrea extract on the immune status in wistar rats / norwati jailani
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Pharmacy
publishDate	2012
url	https://ir.uitm.edu.my/id/eprint/66747/1/66747.pdf
_version_	1783735637544796160

Study of the effects of Myrmecodia platytyrea extract on the immune status in Wistar rats / Norwati Jailani

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