Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor

The purpose of this research is to observe morphological changes on MCF-7 and HCT-116 cell lines treated with aqueous extracts of M. platytyrea from Rubiaceae family. The concentrations of M. platytyrea used in this research are (0.01, 0.1, 0, 1, 10, 100, and 1000 μg/ml). From the result, apoptosis...

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Main Author:	Mohd Noor, Nurul Ain
Format:	Thesis
Language:	English
Published:	2012
Subjects:	Cell culture Lasers
Online Access:	https://ir.uitm.edu.my/id/eprint/66798/1/66798.pdf
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id	my-uitm-ir.66798
record_format	uketd_dc
spelling	my-uitm-ir.667982022-09-15T06:17:42Z Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor 2012 Mohd Noor, Nurul Ain Cell culture Lasers The purpose of this research is to observe morphological changes on MCF-7 and HCT-116 cell lines treated with aqueous extracts of M. platytyrea from Rubiaceae family. The concentrations of M. platytyrea used in this research are (0.01, 0.1, 0, 1, 10, 100, and 1000 μg/ml). From the result, apoptosis were detected in both cells. For HCT-116, the aqueous extract of M. platytyrea induced apoptosis about 10 times higher than the control. Meanwhile, in MCF-7, apoptosis was induced about 47 times higher than the control using the same extract. This further suggested that the aqueous extract of M. platytyrea was more selective to induce apoptosis in breast cancer cells compared to colon cancer cells. 2012 Thesis https://ir.uitm.edu.my/id/eprint/66798/ https://ir.uitm.edu.my/id/eprint/66798/1/66798.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Hasan, Mizaton Hazizul
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Hasan, Mizaton Hazizul
topic	Cell culture Lasers
spellingShingle	Cell culture Lasers Mohd Noor, Nurul Ain Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
description	The purpose of this research is to observe morphological changes on MCF-7 and HCT-116 cell lines treated with aqueous extracts of M. platytyrea from Rubiaceae family. The concentrations of M. platytyrea used in this research are (0.01, 0.1, 0, 1, 10, 100, and 1000 μg/ml). From the result, apoptosis were detected in both cells. For HCT-116, the aqueous extract of M. platytyrea induced apoptosis about 10 times higher than the control. Meanwhile, in MCF-7, apoptosis was induced about 47 times higher than the control using the same extract. This further suggested that the aqueous extract of M. platytyrea was more selective to induce apoptosis in breast cancer cells compared to colon cancer cells.
format	Thesis
qualification_level	Bachelor degree
author	Mohd Noor, Nurul Ain
author_facet	Mohd Noor, Nurul Ain
author_sort	Mohd Noor, Nurul Ain
title	Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_short	Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_full	Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_fullStr	Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_full_unstemmed	Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor
title_sort	morphological changes during programmed cell death (pcd) using laser scanning confocal microscopy / nurul ain mohd noor
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Pharmacy
publishDate	2012
url	https://ir.uitm.edu.my/id/eprint/66798/1/66798.pdf
_version_	1783735640052989952

Morphological changes during programmed cell death (PCD) using laser scanning confocal microscopy / Nurul Ain Mohd Noor

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